Results: 3

Depression and anxiety disorders in patients with multiple sclerosis: association with neurodegeneration and neurofilaments

Braz. j. med. biol. res; 54 (3), 2021
There is increasing evidence that neurofilament light chain (NF-L) can be considered as a biomarker for neuro-axonal damage. This polypeptide can be released into the cerebrospinal fluid (CSF) and the blood, where it can be quantified. The concentration of NF-L is elevated in patients with multiple scler...

A cerebrospinal fluid biosignature for the diagnosis of Alzheimer's disease

Neurofilament light chain in the assessment of patients with multiple sclerosis

Arq. neuropsiquiatr; 77 (6), 2019
ABSTRACT Multiple sclerosis (MS) is an autoimmune, inflammatory, and degenerative disease of the central nervous system. Axonal degeneration is triggered by inflammation and is the pathological substrate of progressive disability in patients with MS. Therapeutic interventions can reduce inflammatory acti...