LILACS – Literatura Latinoamericana y del Caribe de Ciencias de la Salud

Prophylactic application of laser light restores L-FABP expression in the livers of rats submitted to partial ischemia

Vilalva, Kelvin Henrique; Figueira, Rebeca Lopes; Silveira, Marina; Graf, Catarina; Gonçalves, Frances Lanhellas; Sbragia, Lourenço; Gomes, Maria Cecília; Mumic, Fabrícia; Vollet-Filho, José Dirceu; Bagnato, Vanderlei Salvador; D'Albuquerque, Luiz Augusto Carneiro; Castro-e-Silva, Orlando.

Clinics; 73 (), 2018

OBJECTIVES: The objective of the present study was to evaluate the protective effect of pre-conditioning treatment with laser light on hepatic injury in rats submitted to partial ischemia using mitochondrial function and liver fatty acid binding protein as markers. METHODS: Rats were divided into four g...

Alanina Transaminasa/sangre, Aspartato Aminotransferasas/sangre, Western Blotting, Proteínas de Unión a Ácidos Grasos/análisis, Proteínas de Unión a Ácidos Grasos/metabolismo, Precondicionamiento Isquémico/métodos, Hígado/irrigación sanguínea, Hígado/metabolismo, Hígado/efectos de la radiación, Terapia por Luz de Baja Intensidad/métodos, Malondialdehído/análisis, Malondialdehído/efectos de la radiación, Membranas Mitocondriales/efectos de los fármacos, Dilatación Mitocondrial/efectos de la radiación, Ratas Wistar, Daño por Reperfusión/prevención & control, Reproducibilidad de los Resultados

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Temporal profile of intestinal tissue expression of intestinal fatty acid-binding protein in a rat model of necrotizing enterocolitis

Simões, Ana Leda Bertoncini; Figueira, Rebeca Lopes; Gonçalves, Frances Lilian Lanhellas; Mitidiero, Luís Felipe Tsuyoshi; Silva, Orlando Castro e; Peiró, José Luis; Sbragia, Lourenço.

Clinics; 71 (7), 2016

OBJECTIVES: Necrotizing enterocolitis is a severe multifactorial intestinal disorder that primarily affects preterm newborns, causing 20-40% mortality and morbidity. Intestinal fatty acid-binding protein has been reported to be a biomarker for the detection of intestinal injuries. Our aim was to assess i...

Animales Recién Nacidos, Biomarcadores/análisis, Western Blotting, Peso Corporal, Modelos Animales de Enfermedad, Enterocolitis Necrotizante/metabolismo, Enterocolitis Necrotizante/patología, Proteínas de Unión a Ácidos Grasos/análisis, Proteínas de Unión a Ácidos Grasos/metabolismo, Hipoxia/patología, Íleon/irrigación sanguínea, Íleon/patología, Inmunohistoquímica, Isquemia/patología, Distribución Aleatoria, Ratas Sprague-Dawley, Valores de Referencia, Índice de Severidad de la Enfermedad, Factores de Tiempo

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Comparative proteomic analysis of the nucleus accumbens during extinction and reinstatement of morphine dependence

Feng, K; Qiu, H; Gao, Y; Fu, Y; Du, L; Qiu, T; Meng, H; Luo, Q.

West Indian med. j; 62 (3), 2013

BACKGROUND: The aim of this study was to detect differentially expressed proteins in the nucleus accumbens between the states of extinction and reinstatement of morphine addiction. Numerous studies on the neurobiological mechanisms concerning drug craving and relapse have been reported to date, but data ...

Extinción Psicológica/fisiología, Proteínas de Unión a Ácidos Grasos/metabolismo, Proteínas HSP90 de Choque Térmico/metabolismo, Dependencia de Morfina/metabolismo, Núcleo Accumbens/metabolismo, Proteína Fosfatasa 2/metabolismo, Proteoma, Ratas Sprague-Dawley, Refuerzo en Psicología

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