Evaluation of nuclear NF-κB, transglutaminase2, and ERCC1 as predictors of platinum resistance in testicular tumors
Int. braz. j. urol; 46 (3), 2020
ABSTRACT Purpose: Testicular germ cells tumor (TGCT) are associated with a high cure rate and are treated with platinum-based chemotherapy. However, a group of testicular cancer patients may have a very unfavorable evolution and insensitivity to the main therapeutic agent chemotherapy (CT) cisplatin. Th...
Protocolos de Quimioterapia Combinada Antineoplásica, Cisplatino, Reparación del ADN, Proteínas de Unión al ADN, Resistencia a Antineoplásicos/fisiología, Endonucleasas, Proteínas de Unión al GTP/metabolismo, Neoplasias Pulmonares, FN-kappa B/metabolismo, Pronóstico, Estudios Retrospectivos, Neoplasias Testiculares, Transglutaminasas/metabolismo