LILACS – Literatura Latinoamericana y del Caribe de Ciencias de la Salud

Mir-30b-3p affects the migration and invasion function of ovarian cancer cells by targeting the CTHRC1 gene

Li, Yan; Zhou, Jinhua; Wang, Juan; Chen, Xiaoping; Zhu, Yan; Chen, Youguo.

Biol. Res; 53 (), 2020

BACKGROUND: The aim of this study was to investigate the effect role and mechanism of miR-30b-3p on ovarian cancer cells biological function. METHODS: The expression of miR-30b-3p was detected in ovarian cancer cell lines and normal ovarian epithelial cell line by qRT-PCR. Mir-30b-3p mimic was transfecte...

Transición Epitelial-Mesenquimal/genética, Proteínas de la Matriz Extracelular/genética, Regulación Neoplásica de la Expresión Génica/genética, MicroARNs/genética, Neoplasias Ováricas/genética, Proteínas de la Matriz Extracelular/metabolismo, Neoplasias Ováricas/metabolismo, Apoptosis, Línea Celular Tumoral, Movimiento Celular, Proliferación Celular, Invasividad Neoplásica, Transducción de Señal

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Evaluation of the fibulin 5 gene polymorphism as a factor related to the occurrence of pelvic organ prolapse

Paula, Marcus Vinicius Barbosa de; Lira Júnior, Marcos Antônio de Farias; Monteiro, Vivian Costa e Silva Crocco; Souto, Ricardo Peres; Fernandes, César Eduardo; Oliveira, Emerson de.

Rev. Assoc. Med. Bras. (1992, Impr.); 66 (5), 2020

SUMMARY OBJECTIVE Pelvic organ prolapse (POP) is a very frequent situation in our population that may lead to a significant decrease in patients' quality of life. Currently, we are looking for predictive factors for the development of POPs; thus, this study seeks to evaluate whether the Fibulin 5 polym...

Brasil, Proteínas de Unión al Calcio/genética, Estudios de Cohortes, Proteínas de la Matriz Extracelular/genética, Prolapso de Órgano Pélvico, Polimorfismo Genético, Calidad de Vida

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Isolation and characterization of a human cementocyte-like cell line, HCY-23

Almeida, Amanda Bandeira de; Santos, Elis Janaína Lira dos; Abuna, Gabriel Flores; Ribeiro, Cristiane Salmon; Casati, Márcio Zaffalon; Ruiz, Karina Gonzales Silvério; Nociti Júnior, Francisco Humberto.

Braz. oral res. (Online); 33 (), 2019

Abstract Cementum is the mineralized tissue covering the tooth root that functions in tooth attachment and post-eruptive adjustment of tooth position. It has been reported to be highly similar to bone in several respects but remains poorly understood in terms of development and regeneration. Here, we inv...

Proteínas Adaptadoras Transductoras de Señales, Análisis de Varianza, Proteínas Morfogenéticas Óseas/análisis, Proteínas Morfogenéticas Óseas/genética, Técnicas de Cultivo de Célula/métodos, Línea Celular, Cemento Dental/metabolismo, Proteínas de la Matriz Extracelular/análisis, Proteínas de la Matriz Extracelular/genética, Técnica del Anticuerpo Fluorescente, Expresión Génica, Marcadores Genéticos/genética, Glicoproteínas de Membrana/análisis, Glicoproteínas de Membrana/genética, Diente Molar/citología, Fosfatos/farmacología, Fosfoproteínas/análisis, Fosfoproteínas/genética, Sialoglicoproteínas/análisis, Sialoglicoproteínas/genética, Factores de Tiempo, Cemento Dental/citología

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Association between TGFβ1 polymorphisms and chronic hepatitis B infection in an Iranian population

Eskandari, Ebrahim; Metanat, Malihe; Pahlevani, Elham; Nakhzari-Khodakheir, Tooba.

Rev. Soc. Bras. Med. Trop; 50 (3), 2017

Abstract INTRODUCTION: Transforming growth factor-beta 1 (TGFβ1) is a potent suppressive cytokine that contributes to chronic hepatitis B (CHB) infection. Disparities in TGFβ1 production among individuals have been attributed to TGFβ1 genetic polymorphisms. We examined whether three putat...

Estudios de Casos y Controles, Proteínas de la Matriz Extracelular/genética, Frecuencia de los Genes, Predisposición Genética a la Enfermedad, Genotipo, Hepatitis B Crónica/genética, Irán, Persona de Mediana Edad, Polimorfismo Genético, Factor de Crecimiento Transformador beta/genética, Factor de Crecimiento Transformador beta1/genética

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Increased expression of ID2, PRELP and SMOC2 genes in patients with endometriosis

Araujo, F M; Meola, J; Rosa-e-Silva, J C; Paz, C C P; Ferriani, R A; Nogueira, A A.

Braz. j. med. biol. res; 50 (7), 2017

Endometriosis is a benign, estrogen-dependent disease with symptoms such as pelvic pain and infertility, and it is characterized by the ectopic distribution of endometrial tissue. The expression of the ID2, PRELP and SMOC2 genes was compared between the endometrium of women without endometriosis in the p...

Estudios de Casos y Controles, Endometriosis/genética, Endometriosis/metabolismo, Proteínas de la Matriz Extracelular/genética, Proteínas de la Matriz Extracelular/metabolismo, Regulación de la Expresión Génica, Glicoproteínas/genética, Glicoproteínas/metabolismo, Proteína 2 Inhibidora de la Diferenciación/genética, Proteína 2 Inhibidora de la Diferenciación/metabolismo, Ciclo Menstrual, Osteonectina/genética, Enfermedades Peritoneales/genética, Reacción en Cadena en Tiempo Real de la Polimerasa

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Schizophrenia and reelin: a model based on prenatal stress to study epigenetics, brain development and behavior

Negrón-Oyarzo, Ignacio; Lara-Vásquez, Ariel; Palacios-García, Ismael; Fuentealba, Pablo; Aboitiz, Francisco.

Biol. Res; 49 (), 2016

Schizophrenia is a severe psychiatric disorder that results in a significant disability for the patient. The disorder is characterized by impairment of the adaptive orchestration of actions, a cognitive function that is mainly dependent on the prefrontal cortex. This behavioral deficit, together with cel...

Encéfalo/embriología, Moléculas de Adhesión Celular Neuronal/genética, Epigénesis Genética/fisiología, Proteínas de la Matriz Extracelular/genética, Proteínas del Tejido Nervioso/genética, Efectos Tardíos de la Exposición Prenatal/fisiopatología, Esquizofrenia/etiología, Esquizofrenia/fisiopatología, Serina Endopeptidasas/genética, Estrés Fisiológico/fisiología, Encéfalo/fisiopatología, Trastornos del Conocimiento/fisiopatología, Trastorno de la Conducta Social/fisiopatología, Metilación de ADN, Expresión Génica, Factores de Riesgo

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Olfactomedin-like 2 A and B (OLFML2A and OLFML2B) expression profile in primates (human and baboon)

Pérez-Ibave, Diana Cristina; González-Alvarez, Rafael; Martinez-Fierro, Margarita de La Luz; Ruiz-Ayma, Gabriel; Luna-Munoz, Maricela; Martínez-De-Villarreal, Laura Elia; Garza-Rodríguez, María De Lourdes; Reséndez-Pérez, Diana; Mohamed-Noriega, Jibran; Garza-Guajardo, Raquel; Bautista-De-Lucío, Victor Manuel; Mohamed-Noriega, Karim; Barboza-Quintana, Oralia; Arámburo-De-La-Hoz, Carlos; Barrera-Saldana, Hugo Alberto; Rodríguez-Sánchez, Irám Pablo.

Biol. Res; 49 (), 2016

BACKGROUND: The olfactomedin-like domain (OLFML) is present in at least four families of proteins, including OLFML2A and OLFML2B, which are expressed in adult rat retina cells. However, no expression of their orthologous has ever been reported in human and baboon. OBJECTIVE: The aim of this study was to ...

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