ABSTRACT We describe the case of a 15-year-old girl with decreased visual acuity associated with elevated intraocular pressure in both eyes and angle closure on gonioscopy. She also presented attenuation of retinal vessels and optic disc pallor with large excavation in the left eye. Ultrasound biomicrosc...
Abstract Autosomal recessive primary microcephaly (MCPH) is a neurodevelopmental disorder characterized by a congenitally reduced head circumference (-3 to -5 SD) and non-progressive intellectual disability. The objective of the study was to evaluate pathogenic mutations in the ASPM gene to understand et...
Abstract The aim of our study was to isolate populations of keratinocyte stem cells based on the expression of cell surface markers and to investigate whether the culture could affect their phenotype. keratinocytes from human oral mucosa were sorted based on the expression of the epithelial stem cell mar...
Citometría de Flujo/métodos,
Células Epiteliales/citología,
Separación Celular/métodos,
Técnicas de Cultivo de Célula/métodos,
Biomarcadores/análisis,
Antígenos CD/análisis,
Queratinocitos/citología,
Mucosa Bucal/citología,
Proteínas del Tejido Nervioso/análisis,
Fenotipo,
Receptores de Factor de Crecimiento Nervioso/análisis,
Receptores de Transferrina/análisis,
Reproducibilidad de los Resultados,
Células Madre/citología
Abstract Background Cocaine-and amphetamine regulated transcript (CART) is an endogenous neuropeptide, which is widespread in animals, plays a key role in regulation of follicular atresia in cattle and sheep. Among animal ovaries, CART mRNA was firstly found in the cattle ovaries. CART was localized in ...
ABSTRACT Objective To investigate serum nesfatin-1 levels at 24-28 weeks of pregnancy in women newly diagnosed with gestational diabetes and determine the association of nesfatin-1 with several metabolic parameters. Subjects and methods Forty women newly diagnosed with gestational diabetes at 24-28 w...
Biomarcadores/sangre,
Índice de Masa Corporal,
Proteínas de Unión al Calcio/sangre,
Estudios de Casos y Controles,
Estudios Transversales,
Proteínas de Unión al ADN/sangre,
Diabetes Gestacional/sangre,
Diabetes Gestacional/diagnóstico,
Ensayo de Inmunoadsorción Enzimática,
Ayuno/sangre,
Edad Gestacional,
Prueba de Tolerancia a la Glucosa,
Proteínas del Tejido Nervioso/sangre,
Nucleobindinas
Summary Introduction: Prostate cancer is the second type of cancer diagnosed and the fifth cause of death in men worldwide. Early diagnosis helps to control disease progression. Currently, prostate specific antigen is the standard biomarker, as it has a broad scope of identification and, thus, new and m...
BACKGROUND: Cocaine- and amphetamine-regulated transcript (CART), discovered initially by via differential display RT-PCR analysis of brains of rats administered cocaine, is expressed mainly in central nervous system or neuronal origin cells, and is involved in a wide range of behaviors, such as regulati...
Rabies is a lethal disease caused by a neurotropic virus that produces inconspicuous morphological changes hardly observable with conventional histopathology. The fatal outcome caused by rabies could be attributed to specific biochemical changes that severely impact neuronal function. The neuronal nuclea...
Abstract Multicystic and unicystic ameloblastomas are benign odontogenic tumors that present distinct biological behavior. The investigation of stem cells has become an important branch of tumor biology, with several studies addressing the possible role of these cells in tumor growth, angiogenesis, progr...
Ameloblastoma/metabolismo,
Ameloblastoma/patología,
Biomarcadores de Tumor/metabolismo,
Células Endoteliales/metabolismo,
Fibroblastos/metabolismo,
Inmunohistoquímica,
Neoplasias Mandibulares/metabolismo,
Neoplasias Mandibulares/patología,
Persona de Mediana Edad,
Células Madre Neoplásicas/metabolismo,
Células Madre Neoplásicas/patología,
Proteínas del Tejido Nervioso/metabolismo,
Adhesión en Parafina,
Receptores de Factor de Crecimiento Nervioso/metabolismo,
Estadísticas no Paramétricas,
Células del Estroma,
Antígenos Thy-1/metabolismo
Schizophrenia is a severe psychiatric disorder that results in a significant disability for the patient. The disorder is characterized by impairment of the adaptive orchestration of actions, a cognitive function that is mainly dependent on the prefrontal cortex. This behavioral deficit, together with cel...
Encéfalo/embriología,
Moléculas de Adhesión Celular Neuronal/genética,
Epigénesis Genética/fisiología,
Proteínas de la Matriz Extracelular/genética,
Proteínas del Tejido Nervioso/genética,
Efectos Tardíos de la Exposición Prenatal/fisiopatología,
Esquizofrenia/etiología,
Esquizofrenia/fisiopatología,
Serina Endopeptidasas/genética,
Estrés Fisiológico/fisiología,
Encéfalo/fisiopatología,
Trastornos del Conocimiento/fisiopatología,
Trastorno de la Conducta Social/fisiopatología,
Metilación de ADN,
Expresión Génica,
Factores de Riesgo
