Metformin and resveratrol suppress type 2 diabetes mellitus-induced articular cartilage damage in rats associated with the inhibition of inflammation and augmentation of proteoglycans
Int. j. morphol; 40 (1), 2022
SUMMARY: Induction of osteoarthritis (OA) following diabetes is characterized by a sever inflammation of the joints that can lead to disability. The cartilage content of proteoglycans can substantially be reduced, following the induction of diabetes mellitus associated with inflammation as well as knee j...
Metformina/administración & dosificación, Resveratrol/administración & dosificación, Diabetes Mellitus Experimental, Modelos Animales de Enfermedad, Osteoartritis/prevención & control, Hipoglucemiantes/administración & dosificación, Antiinflamatorios/administración & dosificación, Proteoglicanos/efectos de los fármacos, Inflamación