LILACS – Literatura Latinoamericana y del Caribe de Ciencias de la Salud

Biofilm production by clinical isolates of Pseudomonas aeruginosa and structural changes in LasR protein of isolates non biofilm-producing

Lima, Jailton Lobo da Costa; Alves, Lilian Rodrigues; Jacomé, Paula Regina Luna de Araújo; Bezerra Neto, João Pacífico; Maciel, Maria Amélia Vieira; Morais, Marcia Maria Camargo de.

Braz. j. infect. dis; 22 (2), 2018

ABSTRACT Introduction: Biofilm production is an important mechanism for the survival of Pseudomonas aeruginosa and its relationship with antimicrobial resistance represents a challenge for patient therapeutics. P. aeruginosa is an opportunistic pathogen frequently associated to nosocomial infections, es...

Antibacterianos/farmacología, Antiinfecciosos/farmacología, Proteínas Bacterianas/química, Proteínas Bacterianas/genética, Biopelículas/efectos de los fármacos, Biopelículas/crecimiento & desarrollo, Infección Hospitalaria, Farmacorresistencia Bacteriana Múltiple, Reacción en Cadena de la Polimerasa/métodos, Infecciones por Pseudomonas/tratamiento farmacológico, Infecciones por Pseudomonas/microbiología, Pseudomonas aeruginosa/química, Pseudomonas aeruginosa/efectos de los fármacos, Pseudomonas aeruginosa/fisiología, Transactivadores/química, Transactivadores/genética

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High genetic diversity among Pseudomonas aeruginosa and Acinetobacter spp. isolated in a public hospital in Brazil

In Brazil and other regions of the world, Pseudomonas aeruginosa and Acinetobacter spp. have emerged as important agents of nosocomial infection and are commonly involved in outbreaks. The main objective of the present study was to evaluate the genetic relationship among P. aeruginosa and Acinetobacter s...