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Evaluation of the Th17 pathway in psoriasis and geographic tongue

Picciani, Bruna Lavinas Sayed; Domingos, Tábata Alves; Teixeira-Souza, Thays; Fausto-Silva, Anna Karoline; Dias, Eliane Pedra; Carneiro, Sueli.
An. bras. dermatol; 94 (6), 2019
Abstract Background: Psoriasis is a skin-articular disease with unclear etiopathogenesis. It has been suggested that the disease is immune-mediated by T-lymphocytes, predominantly Th17 cells. Similar to psoriasis, geographic tongue is an inflammatory disease with participation of Th17 cells and direct c...
Anticuerpos/análisis, Biopsia, Estudios Transversales, Glositis Migratoria Benigna/inmunología, Glositis Migratoria Benigna/patología, Inmunohistoquímica, Interleucina-17/inmunología, Interleucina-23/inmunología, Interleucina-6/inmunología, Queratinocitos/patología, Psoriasis/inmunología, Psoriasis/patología, Índice de Severidad de la Enfermedad, Células Th17/inmunología, Células Th17/patología
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CD19+ B cell subsets in the peripheral blood and skin lesions of psoriasis patients and their correlations with disease severity

Lu, J; Ding, Y; Yi, X; Zheng, J.
Braz. j. med. biol. res; 49 (9), 2016
T lymphocytes are important in the pathogenesis of psoriasis, and increasing evidence indicates that B cells also play an important role. The mechanisms of action, however, remain unclear. We evaluated the ratios of CD19+ B cells in peripheral blood mononuclear cells (PBMCs) from 157 patients with psoria...
Antígenos CD19/sangre, Antígenos CD19/inmunología, Subgrupos de Linfocitos B/inmunología, Biomarcadores/sangre, Citometría de Flujo, Activación de Linfocitos, Recuento de Linfocitos, Psoriasis/sangre, Psoriasis/inmunología, Índice de Severidad de la Enfermedad
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