Results: 32

Relação entre aspectos psicossomáticos e psoríase

Psoríase é uma dermatose de caráter inflamatório ligado a diversas composições do ser, sendo estas a genética, o sistema imune, o ambiente e o estado mental do paciente, apresentando evidências de ser um quadro clínico multifacetado. A composição da medicina psicossomática empenha-se na rela...

Differential Regulation of Integrin α5 and β4 in Normal and Psoriatic Epidermal Keratinocytes

Abstract Psoriasis is a chronic skin inflammation, characterized by impaired differentiation, hyperproliferation of keratinocytes involving pro-inflammatory factors interleukin (IL)-13/17A, tumor necrosis factor (TNF)-α, interferon (IFN)-γ. Among the integrin family, α5 is important for blood vessel ...

Psoriasis paradójica palmoplantar secundaria al tratamiento de la colitis ulcerosa con adalimumab

Dermatol. argent; 27 (2), 2021
Los anticuerpos anti-TNF-a (tumor necrosis factor alpha) se utilizan para tratar tanto la psoriasis como la enfermedad inflamatoria intestinal (EII). Sin embargo, estos fármacos han sido implicados en la ocurrencia de la psoriasis paradójica en los pacientes sin antecedentes de psorias...

Clinical characteristics and associations of palmoplantar pustulosis: an observational study

An. bras. dermatol; 95 (1), 2020
Abstract Background: Palmoplantar pustulosis is a chronic and relapsing disease of the palms and soles, which is characterized by scattered clusters of pinhead-sized, sterile pustules. Objective: The aim of the present study was to determine demographic features, co-morbidities, and relation of palmopl...

Acrodermatitis continua de Hallopeau y artritis psoriática: reporte de caso

Medwave; 20 (8), 2020
Un hombre de 44 años, previamente sano, consultó por poliartralgias asimétricas de características inflamatorias de tres meses de evolución, que comprometió pequeñas y grandes articulaciones. Poco tiempo después desarrolló pústulas periungueales sobre una base eritematosa y degeneración progre...

Guselkumab in moderate-to-severe plaque psoriasis: effectiveness in real clinical practice

Rev. chil. dermatol; 36 (3), 2020
Introducción: La psoriasis es una enfermedad cutánea inflamatoria crónica inmunomediada que afecta a casi el 1-2% de la población mundial. El tratamiento biológico de la psoriasis moderada a grave ha cambiado el paradigma de manejo de la enfermedad, permitiendo un mejor control de la misma. Métodos...

Effectiveness of short-term physical agents treatment on macroscopic morphology in patients with plaque psoriasis

Int. j. morphol; 37 (4), 2019
Psoriasis is a chronic inflammatory disease that presents skin rashes which can arise through plaques. The aim of this work was to compare the effectiveness of short-term physical agents treatment on macroscopic morphology (area and erythema) in patients with plaque psoriasis. This prospective randomized...

Lack of association between mutation in IL36RN and palmoplantar pustular psoriasis in Chinese patients

An. bras. dermatol; 94 (6), 2019
Abstract Background: Palmoplantar pustulosis is considered to be a localized pustular psoriasis confined to the palms and soles. Mutation of the IL36RN gene, encoding interleukin-36 receptor antagonist (IL-36Ra), is associated with generalized pustular psoriasis, but IL36RN mutations in Chinese palmopla...

Evaluation of the Th17 pathway in psoriasis and geographic tongue

An. bras. dermatol; 94 (6), 2019
Abstract Background: Psoriasis is a skin-articular disease with unclear etiopathogenesis. It has been suggested that the disease is immune-mediated by T-lymphocytes, predominantly Th17 cells. Similar to psoriasis, geographic tongue is an inflammatory disease with participation of Th17 cells and direct c...

Nail psoriasis treated with intralesional methotrexate infiltration

An. bras. dermatol; 94 (4), 2019