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Mechanisms and biomarker candidates in pterygium development

Wanzeler, Ana Cláudia Viana; Barbosa, Italo Antunes França; Duarte, Bruna; Borges, Daniel; Barbosa, Eduardo Buzolin; Kamiji, Danielle; Huarachi, Delma Regina Gomes; Melo, Mônica Barbosa de; Alves, Mônica.
Arq. bras. oftalmol; 82 (6), 2019
ABSTRACT Pterygium pathogenesis has been mainly asso ciated with UV light exposure; however, this association remains quite controversial. The complete mechanism of pterygium also remains to be clarified. Factors such as inflammation, viral infection, oxidative stress, DNA methylation, inflammatory media...
Proteínas Reguladoras de la Apoptosis, Matriz Extracelular, Expresión Génica, Genes Supresores de Tumor, Marcadores Genéticos, Pterigion/genética, Pterigion/metabolismo
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Expression of specificity protein 1 and collagen I in primary pterygial tissues

Jiang, Bo; Wang, Yong; Zhu, Zi-Cheng; Wu, Zhang-You.
Arq. bras. oftalmol; 82 (5), 2019
ABSTRACT Purpose: To determine the expression profiles of the transcription factor specificity protein 1 and collagen I in primary pterygial and normal conjunctival tissues, and to explore the role of specificity protein 1 and collagen I in pterygial development. Methods: The pterygial tissues of 20 pa...
Western Blotting, Células Cultivadas, Colágeno Tipo I/genética, Colágeno Tipo I/metabolismo, Conjuntiva/anomalías, Conjuntiva/metabolismo, Pterigion/genética, Pterigion/metabolismo, ARN Mensajero/genética, ARN Mensajero/metabolismo
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