Objetivou-se avaliar a resistência a contaminações por micro-organismos obtida com a adição do fruto da pimenta-rosa (Schinus terebinthifolius Raddi) em queijo tipo Cottage formulado com leite bovino. Foram analisadas cinco concentrações: T1 – queijo Cottage com (0%) de pimenta-rosa; T2 – que...
Oliveira, Mariana Villas Bôas Vidal de;
Alves, Priscila Elias;
Teixeira, Jessica;
Monteiro, Mariana Sato de Souza de Bustamante;
Moreira, Tailane SantAnna;
Ricci Junior, Eduardo;
Santos, Elisabete Pereira dos;
Santos-Oliveira, Ralph;
Marins, Rita de Cássia Elias Estrela;
Freitas, Zaida Maria Faria de.
Abstract The objective of this paper was to develop and evaluate two semi-solid pharmaceutical forms containing 0.1% tacrolimus: cream (CRT01) and gel (GLT01). For the evaluation of physicochemical stability, at times 0, 30, 60 and 90 days, at 23°C and at 40°C, High Performance Liquid Chromatography co...
Cambuci (Campomanesia phaea Berg) is a native fruit of the Atlantic Coastal Forest, belonging to the Myrtaceae family, rich in ellagitannins (ET), proanthocyanidins and other bioactive phenolic compounds (BPCs) related to beneficial effects to human health, such as systemic inflammation and attenuation o...
A conjuntivite bacteriana tem significante impacto na Saúde Pública. Essa infecção representa mais de um terço das doenças oculares relatadas em âmbito global. É uma doença altamente contagiosa causada por variedade de bactérias aeróbias e anaeróbias. Diferentes antibióticos empregados no tr...
Conjuntivitis Bacteriana/metabolismo,
Nanopartículas/análisis,
Fluoroquinolonas,
Antibacterianos/clasificación,
Cromatografía Líquida de Alta Presión/métodos,
Bacterias Aerobias/clasificación,
Disolución,
Química Física/instrumentación,
Infecciones/tratamiento farmacológico,
Oftalmopatías/patología,
Preparaciones Farmacéuticas,
Química Farmacéutica,
Técnicas In Vitro/instrumentación
A Hipercolesterolemia Familial (HF) é uma doença hereditária do metabolismo lipídico que causa aos portadores alta incidência de aterosclerose prematura. A HF pode ser diagnosticada clínica e geneticamente, entretanto, apenas cerca de 40% podem ter confirmados pelo diagnostico molecular. Assim, out...
The antiparasitic niclosamide has shown promising anticancer activity in preclinical studies against several types of cancer, such as colorectal and prostate. Thus, the objective of this work was to develop innovative formulations for the repositioning of niclosamide as an anticancer agent. In chapter I,...
Abstract The present study is aimed to formulate steroidal oral mucoadhesive gels of dexamethasone sodium phosphate and betamethasone sodium phosphate. Six gel formulations each of dexamethasone sodium phosphate and betamethasone sodium phosphate prepared using two different polymers carboxymethyl cellul...
Abstract The study is aimed at investigating the functional physicochemical and solid state characteristics of food-grade Tetracarpidium conophorum (T. conophorum) oil for possible application in the pharmaceutical industry for drug delivery. The oil was obtained by cold hexane extraction and its physico...
This study aimed at quantifying the occurrence of proteolytic psychotropic microorganisms and total coliforms in refrigerated raw milk, in addition to assessing the quality through its physical-chemical composition. The samples were collected in 10 dairy farms in the municipality of Santa Helena – West...
Leishmaniasis, a neglected tropical disease (NTD), is a set of diseases caused by obligatory parasitic protozoa of the genus Leishmania. And it has cutaneous and visceral eishmaniasis as its main forms. Treatment includes pentavalent antimonials. These drugs have several disadvantages, such as the need f...
Administración Oral,
Leishmaniasis/patología,
Sistema Linfático,
Absorción Gastrointestinal/efectos de los fármacos,
Cromatografía Líquida de Alta Presión/métodos,
Liberación de Fármacos/efectos de los fármacos,
Medicina Tropical/clasificación,
Metodología como un Tema,
Preparaciones Farmacéuticas/análisis,
Técnicas de Cultivo de Célula/instrumentación,
Técnicas In Vitro/instrumentación,
Química Física/clasificación
