SUMMARY: Keloid scar is a unique benign fibroproliferative tumor of the human skin. Previously, it was reported that early growth response 1 (EGR1), a transcription factor, promotes keloid fibrosis; however, the mechanism by which EGR1 modulates keloid formation was not elaborated. In this research, the ...
Fibroblastos,
Queloide/patología,
Transfección,
Queloide/genética,
MicroARNs/fisiología,
Proteína 1 de la Respuesta de Crecimiento Precoz,
Apoptosis,
Reacción en Cadena en Tiempo Real de la Polimerasa,
Western Blotting,
Proliferación Celular,
Movimiento Celular,
Regulación hacia Abajo,
d0347410,
Análisis de Secuencia de ARN,
Cicatrización de Heridas
Abstract Lobomycosis is a chronic granulomatous infection caused by the yeast Lacazia loboi, typically found in tropical and subtropical geographical areas. Transmission occurs through traumatic inoculation into the skin, especially in exposed areas, of men who work in contact with the soil. Lesions are ...
Abstract Histoid leprosy is a rare form of multibacillary leprosy, characterized by the presence of papules, plaques, or nodules whose appearance is keloid-like, skin colored, or erythematous. Fusiform cells are the main histopathological feature. Due to the fact that it can simulate other dermatological...
Abstract We report a 74-year-old male presented to an outpatient dermatology clinic in Manaus, Amazonas, with a one-year history of pruritic, keloidal lesions on his left lower extremity. Histopathology showed round structures in reticular dermis. Grocott methenamine silver stain revealed numerous round ...
Biopsia,
Carcinoma Basocelular/etiología,
Carcinoma Basocelular/patología,
Carcinoma de Células Escamosas/etiología,
Carcinoma de Células Escamosas/patología,
Cicatriz Hipertrófica/complicaciones,
Cicatriz Hipertrófica/patología,
Queloide/complicaciones,
Queloide/patología,
Neoplasias Cutáneas/etiología,
Neoplasias Cutáneas/patología
Abstract: Lobomycosis or lacaziosis is a chronic granulomatous fungal infection caused by Lacazia loboi. Most cases are restricted to tropical regions. Transmission is believed to occur through traumatic inoculation in the skin, mainly in exposed areas. It is characterized by keloid-like nodules. There a...
Antifúngicos/uso terapéutico,
Biopsia,
Clofazimina/uso terapéutico,
Crioterapia/métodos,
Diagnóstico Diferencial,
Enfermedades del Oído/diagnóstico,
Enfermedades del Oído/patología,
Enfermedades del Oído/terapia,
Itraconazol/uso terapéutico,
Queloide/diagnóstico,
Queloide/patología,
Lobomicosis/diagnóstico,
Lobomicosis/patología,
Lobomicosis/terapia,
Resultado del Tratamiento
Scar formation is a consequence of the wound healing process that occurs when body tissues are damaged by a physical injury. Hypertrophic scars and keloids are pathological scars resulting from abnormal responses to trauma and can be itchy and painful, causing serious functional and cosmetic disability. ...
Corticoesteroides/uso terapéutico,
Bleomicina/uso terapéutico,
Cicatriz Hipertrófica/etiología,
Cicatriz Hipertrófica/patología,
Cicatriz Hipertrófica/terapia,
Trajes Gravitatorios,
Inyecciones Intralesiones,
Queloide/patología,
Queloide/terapia,
Geles de Silicona/uso terapéutico,
Cicatrización de Heridas
In a previous study, the authors inoculated Swiss mice with Lacazia loboi (L. loboi) and succeeded in maintaining a granulomatous infiltrate and viable fungal cells up to one year and six months after inoculation. Considering the experimental work on paracoccidioidomycosis, 0.03 ml of a fungal suspension...
