Normal wound healing occurs in four overlapping stages - hemostasis, inflammation, proliferation, and remodeling. In the oral cavity, these processes occur in an infectious environment. Among the pathogens found in the oral community, Aggregatibacter actinomycetemcomitans (Aa) constitutes a well-recogniz...
SUMMARY: The skin, located on the outermost part of the body, is always exposed to external stimuli such as sunlight. The exposure of skin to ultraviolet B (UVB) radiation from sunlight is known to be a major environmental factor in inducing photoaging. After exposure to UVB, an increase in reactive oxyg...
The solar ultraviolet (UV) radiation that reaches the Earth is composed of 95% of UVA (320 to 400 nm) and 5% of UVB (280 to 320 nm) radiation. UVB is carcinogenic, generating potentially mutagenic DNA lesions. The solar UVA radiation also causes DNA damage, but this fact does not fully account for its bi...
Proteómica/clasificación,
Queratinocitos/química,
Rayos Ultravioleta/efectos adversos,
Antioxidantes/efectos adversos,
Células Epiteliales/clasificación,
Células HaCaT/clasificación,
ADN,
Dosis de Radiación,
Espectrometría de Masas/métodos,
Genotoxicidad/efectos adversos,
Piel
Zhao, Dan;
Xiao, Jinli;
Qiang, Lijuan;
Deng, Xingwang;
An, Jingjing;
Zhang, Qing;
Zhao, Fang;
Ma, Jiaxiang;
Fang, Chao;
Guan, Guangyu;
Wu, Yinsheng;
Xie, Yan.
Purpose:
To investigate the active ingredients of walnut ointment (WO) and its mechanism in repairing wounds.
Methods:
The ingredients of WO were detected by gas chromatography–mass spectrometry. The effect of linoleic acid (LA) was tested by in vitro Alamar Blue (AB) reagent. Image J software, histol...
Abstract Psoriasis is a chronic skin inflammation, characterized by impaired differentiation, hyperproliferation of keratinocytes involving pro-inflammatory factors interleukin (IL)-13/17A, tumor necrosis factor (TNF)-α, interferon (IFN)-γ. Among the integrin family, α5 is important for blood vessel ...
Abstract Currently, pagetoid dyskeratosis is believed to involve an accelerated keratinization process, possibly induced by mechanical trauma. It represents, in almost its totality, incidental histological findings of specific cells, except when it occurs in the hands, where it usually occurs simultaneou...
Souza, T F G;
Pierdoná, T M;
Macedo, F S;
Aquino, P E A;
Rangel, G F P;
Duarte, R S;
Silva, L M A;
Viana, G S B;
Alves, A P N N;
Montenegro, R C;
Wilke, D V;
Silveira, E R;
Alencar, N M N.
It was previously demonstrated that the methanol fraction of Sideroxylon obtusifolium (MFSOL) promoted anti-inflammatory and healing activity in excisional wounds. Thus, the present work investigated the healing effects of MFSOL on human keratinocyte cells (HaCaT) and experimental burn model injuries. Ha...
SUMMARY: The treatment of chronic wounds has become a public health issue in recent years mainly due to comorbidities associated with an older population and bacterial resistance. Honey has emerged as an alternative treatment for chronic wounds but lack of knowledge of its mechanism of actionin the treat...
Resumen Introducción: El jabón para el aseo cutáneo es de empleo común entre la población, sin embargo, es posible que cause daño a las células de la piel y modifique la barrera cutánea. Objetivo: Determinar el efecto citotóxico de los jabones en queratinocitos cultivados in vitro y correlacio...
Agua Corporal,
Células Cultivadas,
Colorimetría,
Dermatitis Irritante/etiología,
Eritema/inducido químicamente,
Voluntarios Sanos,
Concentración de Iones de Hidrógeno,
Irritantes/efectos adversos,
Queratinocitos/efectos de los fármacos,
Piel/efectos de los fármacos,
Pruebas de Irritación de la Piel,
Jabones/efectos adversos,
Jabones/química
