Results: 2

Differential Regulation of Integrin α5 and β4 in Normal and Psoriatic Epidermal Keratinocytes

Zhou, Jiong; Shen, Ji-Yang; Man, Xiao-Yong; Li, Wei; Chen, Jia-Qi; Cai, Sui-Qing; Zheng, Min.

Braz. J. Pharm. Sci. (Online); 58 (), 2022

Abstract Psoriasis is a chronic skin inflammation, characterized by impaired differentiation, hyperproliferation of keratinocytes involving pro-inflammatory factors interleukin (IL)-13/17A, tumor necrosis factor (TNF)-α, interferon (IFN)-γ. Among the integrin family, α5 is important for blood vessel ...

Queratinocitos/clasificación, Psoriasis/patología, Western Blotting/instrumentación, Citocinas/agonistas, Interleucinas/análisis, Integrinas/análisis, Pacientes/clasificación

Fulltext

Photosensitization of Lipofuscin in Skin Keratinocytes: Effect of Visible Light on Human Skin

Tonolli, Paulo Newton.

Lipofuscin is an autofluorescent pigment progressively accumulated during cellular aging, in several tissues, such as heart, muscle and retina, especially in the postmitotic period. That phenomenon may result from oxidative stress, when biomolecules and organelles (mainly mitochondria) are damaged, gener...

Piel, Queratinocitos/clasificación, Lipofuscina/efectos adversos, Luz/efectos adversos, Rayos Ultravioleta/efectos adversos, Lipofuscina, Lisosomas

Fulltext