Quinolinotriazole antiplasmodials via click chemistry: synthesis and in vitro studies of 7-Chloroquinoline-based compounds
Braz. J. Pharm. Sci. (Online); 57 (), 2021
Malaria is nowadays one of the most serious health concerns in a global scale and, although there is an evident increase in research studies in this area, pointed by the vast number of hits and leads, it still appears as a recurrent topic every year due to the drug resistance shown by the parasite exposi...
Antimaláricos/análisis, Plasmodium falciparum/metabolismo, Técnicas In Vitro/instrumentación, Cloroquina/administración & dosificación, Concentración 50 Inhibidora, Malaria/tratamiento farmacológico, Investigación/clasificación, Quimera/anomalías, Química Clic, Resistencia a Medicamentos/efectos de los fármacos