LILACS – Literatura Latinoamericana y del Caribe de Ciencias de la Salud

IL-17A, MCP-1, CCR-2, and ABCA1 polymorphisms in children with non-alcoholic fatty liver disease

Akbulut, Ulas Emre; Emeksiz, Hamdi Cihan; Citli, Senol; Cebi, Alper Han; Korkmaz, Hatice Ayca Ata; Baki, Gaye.

J. pediatr. (Rio J.); 95 (3), 2019

Abstract Objective: The prevalence of non-alcoholic fatty liver disease in children has risen significantly, owing to the worldwide childhood obesity epidemic in the last two decades. Non-alcoholic fatty liver disease is closely linked to sedentary lifestyle, increased body mass index, and visceral adip...

Transportador 1 de Casete de Unión a ATP/genética, Índice de Masa Corporal, Quimiocina CCL2/genética, Predisposición Genética a la Enfermedad, Genotipo, Interleucina-17/genética, Enfermedad del Hígado Graso no Alcohólico/complicaciones, Enfermedad del Hígado Graso no Alcohólico/genética, Obesidad Infantil/complicaciones, Polimorfismo Genético/genética, Receptores CCR2/genética

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Association between MCP-1 -2518A>G polymorphism and asthma susceptibility: a meta-analysis

Chen, Wenli; Cui, Jiewei; Xiang, Guoan; Zhang, Jianpeng; Gao, Hongmei.

Braz. j. med. biol. res; 52 (11), 2019

The published data on the association between MCP-1 -2518A>G polymorphism and asthma susceptibility are inconclusive. Therefore, we performed a meta-analysis to estimate the impact of MCP-1 -2518A>G polymorphism on asthma susceptibility. PubMed, Web of Science, Wanfang, and China National Knowledge...

Población Negra/genética, Asma/genética, Quimiocina CCL2/genética, Población Blanca/genética, Frecuencia de los Genes/genética, Estudios de Asociación Genética, Predisposición Genética a la Enfermedad/genética, Polimorfismo Genético/genética, Factores Protectores, Factores de Riesgo

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A possible association between the -2518 A>G MCP-1 polymorphism and insulin resistance in school children

Matia-García, Inés; Salgado-Goytia, Lorenzo; Ramos-Arellano, Luz Elena; Muñoz-Valle, José Francisco; Armenta-Solís, Adakatia; Garibay-Cerdenares, Olga Lilia; Ramírez, Mónica; Parra-Rojas, Isela.

Arch. endocrinol. metab. (Online); 62 (1), 2018

ABSTRACT Objective Monocyte chemoattractant protein 1 (MCP-1) has been suggested to be involved in the pathophysiology of insulin resistance (IR); therefore, variants in the MCP-1 gene may contribute to the development of this disease. The aim of this study was to analyze the relationship of the -2518 A...

Estudios de Casos y Controles, Quimiocina CCL2/genética, Estudios Transversales, Frecuencia de los Genes, Marcadores Genéticos/genética, Predisposición Genética a la Enfermedad, Genotipo, Resistencia a la Insulina/genética, Polimorfismo de Nucleótido Simple/genética

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The role of MCP-1-CCR2 ligand-receptor axis in chondrocyte degradation and disease progress in knee osteoarthritis

Xu, Yuan-kun; Ke, Yan; Wang, Bin; Lin, Jian-hao.

Biol. Res; 48 (), 2015

BACKGROUND: Osteoarthritis (OA) is a common arthritic disease and multifactorial whole-joint disease. Interactions of chemokines and OA is inadequately documented. RESULTS: In vivo and in vitro studies were conducted to investigate monocyte chemoattractant protein 1 (MCP-1) and receptor chemokine (C-C mo...

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