LILACS – Literatura Latinoamericana y del Caribe de Ciencias de la Salud

Sex differences on solid organ histological characteristics after brain death1

Simão, Raif Restivo; Ferreira, Sueli Gomes; Kudo, Guilherme Konishi; Armstrong Junior, Roberto; Silva, Luiz Fernando Ferraz da; Sannomiya, Paulina; Breithaupt-Faloppa, Ana Cristina; Moreira, Luiz Felipe Pinho.

Acta cir. bras; 31 (4), 2016

PURPOSE: To investigate gender differences in the evolution of the inflammatory process in rats subjected to brain death (BD). METHODS: Adult Wistar rats were divided into three groups: female; ovariectomized female; and male rats. BD was induced using intracranial balloon inflation and confirmed by ma...

Muerte Encefálica/patología, Riñón/patología, Hígado/patología, Pulmón/patología, Miocardio/patología, Caracteres Sexuales, Quimiocina CXCL1/análisis, Quimiocina CXCL2/análisis, Edema/patología, Estradiol/sangre, Inflamación/patología, Especificidad de Órganos, Ovariectomía, Progesterona/sangre, Ratas Wistar, Valores de Referencia, Factores Sexuales, Factores de Tiempo

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Optimization of transgenesis conditions for the generation of CXCL2-luciferase reporter mice line

Background: Transgenesis by microinjection has been widely used for the generation of different mouse models. Different variables of the procedure may critically affect the efficiency of the process. A DNA construction that carries the CXCL2 promoter gene and firefly luciferase has been used to optimize ...