Abstract INTRODUCTION The nematode Caenorhabditis elegans was used as a biological sensor to detect the urine of sepsis patients (CESDA assay). METHODS C. elegans was aliquoted onto the center of assay plates and allowed to migrate towards sepsis (T) or control (C) urine samples spotted on the same pl...
BACKGROUND: Chemokine (C-C motif) receptor 6 (CCR6) is present in sperm and plays a significant role in sperm motility and chemotaxis acting in the reproductive tracts. However, the expression and functional significance of CCR6 in testis are still poorly understood, especially in the process of spermato...
Quimiocina CCL20/metabolismo,
Quimiotaxis/fisiología,
Receptores CCR6/metabolismo,
Espermatogénesis/fisiología,
Criptorquidismo/metabolismo,
Motilidad Espermática/fisiología,
Testículo/fisiología,
Western Blotting,
Técnica del Anticuerpo Fluorescente,
Inmunohistoquímica,
Ratones Endogámicos C57BL,
Células de Sertoli
Abstract Biomphalaria amazonica is a planorbid species considered a potential host of Schistosoma mansoni. It is widely distributed in the Neotropical zone, particularly in the North and Centre-West of Brazil and in the North of Bolivia. The aim of the present study was to determine the host-parasite rel...
Deciduous teeth exfoliate as a result of apoptosis induced by cementoblasts, a process that reveals the mineralized portion of the root while attracting clasts. Root resorption in deciduous teeth is slow due to lack of mediators necessary to speed it up; however, it accelerates and spreads in one single ...
Apoptosis/fisiología,
Resorción Ósea/fisiopatología,
Quimiotaxis/fisiología,
Cemento Dental/fisiología,
Saco Dental/citología,
Saco Dental/fisiología,
Factor de Crecimiento Epidérmico/fisiología,
Células Epiteliales/fisiología,
Péptidos y Proteínas de Señalización Intercelular/fisiología,
Odontoblastos/fisiología,
Métodos de Anclaje en Ortodoncia/métodos,
Resorción Radicular/fisiopatología,
Erupción Dental/fisiología,
Exfoliación Dental/fisiopatología,
Técnicas de Movimiento Dental/métodos,
Diente Primario/fisiología
Background Activation of the complement system plays an important role in the regulation of immune and inflammatory reactions, and contributes to inflammatory responses triggered by envenomation provoked byBothrops snakes. The present study aimed to assess whether Bothrops jararacussuand Bothrops pirajai...
Background The skin secretions of toads of the family Bufonidae contain biogenic amines, alkaloids, steroids (bufotoxins), bufodienolides (bufogenin), peptides and proteins. The poison of Rhinella schneideri, formerly classified as Bufo paracnemis, presents components that act on different biological sys...
Diabetic retinopathy is one of the most important causes of blindness. The underlying mechanisms of this disease include inflammatory changes and remodeling processes of the extracellular-matrix (ECM) leading to pericyte and vascular endothelial cell damage that affects the retinal circulation. In turn, ...
Retinopatía Diabética/tratamiento farmacológico,
Inhibidores de Serina Proteinasa/uso terapéutico,
alfa 1-Antitripsina/uso terapéutico,
Antiinflamatorios/metabolismo,
Antiinflamatorios/uso terapéutico,
Movimiento Celular/fisiología,
Quimiotaxis/fisiología,
Retinopatía Diabética/fisiopatología,
Inflamación/metabolismo,
Mediadores de Inflamación/antagonistas & inhibidores,
FN-kappa B/metabolismo,
Neutrófilos/fisiología,
Óxido Nítrico Sintasa/antagonistas & inhibidores,
Sustancias Protectoras/metabolismo,
Receptores Proteinasa-Activados/metabolismo,
Inhibidores de Serina Proteinasa/metabolismo,
Factor de Necrosis Tumoral alfa/metabolismo,
alfa 1-Antitripsina/metabolismo,
Hipoxia de la Célula,
Radicales Libres
Fatores de crescimento polipeptídicos são proteínas de baixo peso molecular sintetizadas por várias células e tecidos que regulam os eventos básicos que levam à regeneração periodontal: proliferação, quimiotaxia, diferenciação e síntese de matriz protéica. Embora diversos métodos terapêu...
En esta revision se describen, de manera esquematica, los mecanismos de accion empleados por los Segundos Mensajeros comenzando por el estimulo del receptor y continuando con las reacciones en cadena que conducen finalmente a una respuesta celular....