Hypothermia treatment reduced cyclin-dependent kinase 5-mediated inflammation in ischemic stroke and improved outcomes in ischemic stroke patients
Clinics; 75 (), 2020
Results: 2
Hypothermia treatment ameliorated cyclin-dependent kinase 5-mediated inflammation in ischemic stroke and improved outcomes in ischemic stroke patients
Clinics; 74 (), 2019
OBJECTIVES: The inflammatory response is a key mechanism of neuronal damage and loss during acute ischemic stroke. Hypothermia has shown promise as a treatment for ischemic stroke. In this study, we investigated the molecular signaling pathways in ischemic stroke after hypothermia treatment. METHODS: Cy...
Enfermedad Aguda, Biomarcadores/sangre, Western Blotting, Isquemia Encefálica/sangre, Isquemia Encefálica/terapia, Quinasa 5 Dependiente de la Ciclina/sangre, Modelos Animales de Enfermedad, Ensayo de Inmunoadsorción Enzimática, Hipotermia Inducida/métodos, Inflamación/sangre, Interleucina-1beta/sangre, FN-kappa B/sangre, Ratas Sprague-Dawley, Resultado del Tratamiento