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Immunohistochemistry analysis of checkpoint kinase 2 in oral squamous cell carcinoma

Cardoso, Suziene Caroline Silva; Duarte, Andressa; Almeida, Luciana Yamamoto de; León, Jorge Esquiche; Ribeiro-Silva, Alfredo.
Appl. cancer res; 40 (), 2020
Background: Oral squamous cell carcinoma (OSCC) is the most frequently occurring malignant tumor of the head and neck region. Chk2 (Checkpoint kinase 2) is considered a tumor suppressor gene that acts on the cellular response to DNA damage. However, the role of Chk2 in OSCC prognosis is not yet fully und...
Neoplasias de la Boca/metabolismo, Carcinoma de Células Escamosas/metabolismo, Inmunohistoquímica, Quinasa de Punto de Control 2/metabolismo, Análisis de Supervivencia, Pronóstico
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Frequency of Variants in DNA-Repair Genes in a Southwest Colombian Population

García-Perdomo, Herney Andrés; Bedoya Saldarriaga, Mailyn Alejandra; Sánchez, Adalberto.
urol. colomb. (Bogotá. En línea); 28 (3), 2019
Objective To describe the frequency of mutations in DNA-repair genes in a southwestern Colombian population. Methods We have designed an observational study, including 162 people from all ages from southwest Colombia. We have extracted and collected their DNA in filters. We have immersed the DNA in a...
Colombia, ADN, Articulación Temporomandibular, Ataxia Telangiectasia, Molécula de Adhesión Celular Epitelial, Genes, Neoplasias, Polimorfismo de Nucleótido Simple, Programas Informáticos, Proteínas MutS, Proteínas de Homeodominio, Quinasa de Punto de Control 2, Reparación de la Incompatibilidad de ADN, Reparación del ADN
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