Rare complications of multikinase inhibitor treatment
Arch. endocrinol. metab. (Online); 62 (6), 2018
ABSTRACT Objective: The advent of multikinase inhibitor (MKI) therapy has led to a radical change in the treatment of patients with advanced thyroid carcinoma. The aim of this manuscript is to communicate rare adverse events that occurred in less than 5% of patients in clinical trials in a subset of pat...
Antineoplásicos/efectos adversos, Carcinoma/tratamiento farmacológico, Carcinoma Medular/tratamiento farmacológico, Estudios de Seguimiento, Insuficiencia Cardíaca/inducido químicamente, Perforación Intestinal/inducido químicamente, Estimación de Kaplan-Meier, Ooforitis/inducido químicamente, Compuestos de Fenilurea/efectos adversos, Piperidinas/efectos adversos, Inhibidores de Proteínas Quinasas/efectos adversos, Quinazolinas/efectos adversos, Quinolinas/efectos adversos, Estudios Retrospectivos, Factores de Riesgo, Sorafenib/efectos adversos, Trombocitopenia/inducido químicamente, Neoplasias de la Tiroides/tratamiento farmacológico, Factores de Tiempo