Results: 8

Efecto de las membranas con Cu(II) sobre el proceso de filtración y capacidad de biocida contra Escherichia coli

Cienc. tecnol. salud; 9 (1), 2022
Esta investigación estudió la preparación de membranas compuestas de celulosa y quitosano entrecruzadas con Cu(II) para determinar su efecto biocida y eficiencia en la remoción deEscherichia coli. Las membranas de quitosano se obtuvieron por medio de la técnica de evaporación del solvente. Propieda...

Chitosan level effects on fermentation profile and chemical composition of sugarcane silage

This study aimed to evaluate the effects of increasing levels of chitosan (CHI) on sugarcane fermentation profile and losses, chemical composition, and in situ degradation. Treatments were: 0, 1, 2, 4, and 8 g of CHI/kg of dry matter (DM). Twenty experimental silos (PVC tubing with diameter 28 cm and hei...

Controlled release alginate-chitosan microspheres of tolmetin sodium prepared by internal gelation technique and characterized by response surface modeling

Tolmetin sodium (TS) is a powerful non-steroidal mitigating drug for the treatment of rheumatoid joint inflammation, osteoarthritis, and adolescent rheumatoid joint pain. In addition to its gastrointestinal (GIT) problems, TS has a short biological half-life (1 hr). In a trial to overcome these side effe...

Otimização e padronização de processos para obtenção de quitosana purificada para uso farmacêutico e alimentício

Quitosana é um biopolímero encontrado principalmente na parede celular de crustáceos e é obtida pela desacetilação da quitina. Como biopolímero a quitosana é utilizada como excipiente para medicamentos e composição de alimentos. No entanto a quitosana devidamente purificada para uso farmacêuti...

Chitosan and carboxymethylated derivative nanoparticles as delivery systems for biological products: preparation, characterization, stability and in vitro/in vivo evaluation

Chitosan is a biocompatible and biodegradable mucoadhesive polymer with unique advantages, such as the distinct trait of opening the junctions to allow paracellular transport of antigen and good tolerability. However, the poor solubility of chitosan in neutral or alkalinized media has restricted its appl...

Vetorização de compostos 5-nitro-heterocí­clicos com atividade frente a microrganismos multirresistentes. Obtenção de nanopartí­culas carregadas e avaliação da atividade antimicrobiana

Pacientes com queimaduras e outras lesões cutâneas de grande extensão apresentam alta propensão a infecções multirresistentes. Neste contexto, o objetivo deste trabalho é a obtenção de nanopartículas de quitosana carregadas com composto derivado de 5-nitro-heterocíclico com estrutura análoga ...

Fabrication and in vitro characterization of polymeric nanoparticles for Parkinson's therapy: a novel approach

Braz. j. pharm. sci; 50 (4), 2014
The objective of the research was to formulate and evaluate selegiline hydrochloride loaded chitosan nanoparticles for the Parkinson's therapy in order to improve its therapeutic effect and reducing dosing frequency. Taguchi method of design of experiments (L9 orthogonal array) was used to get optimized ...

Preparation and characterization of microcapsules of Pterodon pubescens Benth. by using natural polymers

Braz. j. pharm. sci; 50 (4), 2014
An oleaginous fraction obtained from an alcohol extract of the fruit of Pterodon pubescens Benth. (FHPp) was microencapsulated in polymeric systems. These systems were developed using a complex coacervation method and consisted of alginate/medium-molecular-weight chitosan (F1-MC), alginate/chitosan with ...