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Entry of rabies virus in the olfactory bulb of mice and effect of infection on cell markers of neurons and astrocytes

Torres-Fernández, Orlando; Daza, Natalia Andrea; Santamaría-Romero, Gerardo; Hurtado, Andrea P; Monroy-Gómez, Jeison.
Int. j. morphol; 36 (2), 2018
There are few studies of infection by rabies virus in the olfactory bulb (OB). This work was carried out with the purpose of establishing the time required to detect rabies antigens in the OB of mouse, after the intramuscular inoculation of the virus and to evaluate the effect of the infection on the exp...
Rabia/metabolismo, Bulbo Olfatorio/metabolismo, Bulbo Olfatorio/virología, Inmunohistoquímica, Calbindinas/metabolismo, Parvalbúminas/metabolismo, Proteína Ácida Fibrilar de la Glía/metabolismo
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Differential effect of the route of inoculation of rabies virus on NeuN immunoreactivity in the cerebral cortex of mice

Rengifo, Aura Caterine; Umbarila, Vanessa Jazmin; Garzón, Mary Janeth; Torres-Fernández, Orlando.
Int. j. morphol; 34 (4), 2016
Rabies is a lethal disease caused by a neurotropic virus that produces inconspicuous morphological changes hardly observable with conventional histopathology. The fatal outcome caused by rabies could be attributed to specific biochemical changes that severely impact neuronal function. The neuronal nuclea...
Virus de la Rabia/patogenicidad, Corteza Cerebral/patología, Corteza Cerebral/virología, Inmunohistoquímica, Rabia/metabolismo, Corteza Cerebral/metabolismo, Virus de la Rabia/metabolismo, Proteínas del Tejido Nervioso/análisis, Proteínas Nucleares/análisis
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