In mammals, ivermectin acts as a GABAA receptor agonist and stimulates GABA release. Previous studies showed that ivermectin (IVM) reduces sexual performance, impairing the latency to the first mount and intromission. These parameters are usually considered motivational parameters o...
ABSTRACT Solanum guaraniticum is a medicinal plant traditionally used to treat gastric and liver diseases. However, there is no documented evidence corroborating its safety. The present study evaluated the potential toxicity of S. guaraniticum leaf extract after acute administration in rats. Single doses...
Cascas de angico (Piptadenia colubrina Bth) foram coletadas na regiäo do Alto Paranaiba/Minas Gerais e submetidas a processos de extraçäo e liofilizaçäo. O extrato foi empregado em testes farmacológicos com camundongos e ratos machos albinos. Observou-se que doses variáveis do extrato provocaram s...