Yu, Zhangjie;
Peng, Fang;
Liu, Hanxuan;
Qiu, Yinyin;
Ye, Chunji;
Peng, Jiahao;
Xu, Buyun;
Qi, Ying;
Zhou, Yan;
Tang, Weiliang.
This study investigates the efficacy and mechanisms of Kuanxiong Aerosol (KXA) on coronary microvascular dysfunction (CMD) in rats. Thirty-two Sprague-Dawley rats were divided into control, model, KXA, and nicorandil groups, receiving respective treatments for three weeks. The CMD...
Diabetic neuropathy (DN) is a chronic diabetic complication, which is difficult to manage. The current investigation evaluates the effect of Nerium oleander (NO) in the management of diabetic neuropathy (DN). Diabetic neuropathy was induced by streptozotocin (STZ) [60 mg/kg, i.p.] and treated ...
Neuropatías Diabéticas/tratamiento farmacológico,
Mediadores de Inflamación,
Nerium/química,
Modelos Animales de Enfermedad,
Estrés Oxidativo/efectos de los fármacos,
Extractos Vegetales/administración & dosificación,
Extractos Vegetales/farmacología,
Ratas Sprague-Dawley,
Peso Corporal/efectos de los fármacos,
Glucemia/efectos de los fármacos,
Motilidad Gastrointestinal/efectos de los fármacos,
Contracción Muscular/efectos de los fármacos
SUMMARY: Aging is an inevitable biological process that affects the function of all organs, including the adrenal gland, which is essential for producing steroid hormones that regulate metabolism, stress response, and immune activation. Understanding how aging affects the morphology of this gland is cruc...
SUMMARY: Underage drinking has become a major public concern having a negative impact on the growth and development of the skeleton. Peak bone mass is attained during adolescence hence the aim of the study was to investigate the effect of acute binge alcohol consumption on trabecular morphometry and tens...
Consumo Excesivo de Bebidas Alcohólicas,
Mandíbula/efectos de los fármacos,
Resistencia a la Tracción,
Ratas Sprague-Dawley,
Hueso Esponjoso/efectos de los fármacos,
Factores Sexuales,
Nivel de Alcohol en Sangre,
Fenómenos Biomecánicos,
Densidad Ósea,
Modelos Animales de Enfermedad,
Etanol/toxicidad
Objective: To evaluate the effect of melatonin as a protective treatment for the tongue in irradiated rats. Materials and Methods: Male Sprague Dawley rats were subjected to a single session of 50 Gy radiation and treated with melatonin 30 minutes before and after the radiotherapy session. A clinical eva...
Melatonina/uso terapéutico,
Radioterapia/efectos adversos,
Enfermedades de la Lengua/tratamiento farmacológico,
Ratas Sprague-Dawley,
Modelos Animales,
Lengua/efectos de la radiación,
Mucosa Bucal/efectos de la radiación,
Estomatitis/tratamiento farmacológico,
Estomatitis/patología,
Enfermedades de la Lengua/patología,
Estomatitis/etiología,
Enfermedades de la Lengua/etiología,
Protección Radiológica
SUMMARY: Binge drinking in adolescents has a negative effect on the developing skeleton and the attainment of peak bone mass. Our study aimed to examine the effect of binge drinking on the growth and functional integrity of the adolescent Sprague Dawley rat mandible and to determine if a dosage of 1.5 g/...
SUMMARY: The study explores the relationship between chronic exposure to fine particulate matter (PM2.5), sourced from wood smoke, and the histological structure and endocrine function of the uterus in nulliparous adult rats. It assesses potential structural changes in the uterus that could impact reprod...
SUMMARY: Systemic inflammatory response syndrome (SIRS) is a potentially fatal reaction to various forms of tissue damage and infections that cause damage to various organs. Furthermore, the brain is damaged earlier than other organs, resulting in diffuse brain dysfunction. The central clinical symptom o...
SUMMARY: Excessive alcohol consumption adversely affects bone metabolism, thus resulting in reduced bone length, density, and strength. Moreover, these deficits in bone density and strength are likely to increase the risk of fragility fractures and the early onset of osteoporosis. While excessive alcohol...
SUMMARY: We evaluated the role and mechanism of acteoside in the regulation of memory impairment induced by chronic unpredictable mild stress (CUMS). CUMS was used to induce depression in rats and the successful establishment of CUMS model were verified by forced swimming test and sucrose preference test...
Estrés Psicológico/complicaciones,
Trastornos de la Memoria/tratamiento farmacológico,
Glucósidos/administración & dosificación,
Glucósidos/uso terapéutico,
Polifenoles/administración & dosificación,
Polifenoles/uso terapéutico,
Reconocimiento en Psicología/efectos de los fármacos,
Plasticidad Neuronal/efectos de los fármacos,
Serina-Treonina Quinasas TOR/antagonistas & inhibidores,
Depresión/tratamiento farmacológico,
Modelos Animales de Enfermedad,
Ratas Sprague-Dawley,
Escala de Evaluación de la Conducta,
Neuronas,
Técnica del Anticuerpo Fluorescente,
Western Blotting,
Aprendizaje por Laberinto,
Inhibidores mTOR
