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Triple-negative breast cancer cells respond to T cells severely at the alternative splicing layer

Zhao, Lina; Yang, Xi; Feng, Chun; Wang, Yue; Wang, Qing; Pei, Jiahong; Wu, Jinting; Li, Shuaiying; Zhang, Honglei; Cao, Xianbao.
Electron. j. biotechnol; 50 (), 2021
BACKGROUND: Cross talk of tumor–immune cells at the gene expression level has been an area of intense research. However, it is largely unknown at the alternative splicing level which has been found to play important roles in the tumor–immune microenvironment. RESULTS: Here, we re-exploited one transc...
Neoplasias de la Mama Triple Negativas, Linfocitos T, Empalme Alternativo, Transcriptoma, Técnicas de Cultivo de Célula, Aminoacilación de ARN de Transferencia, Inmunoterapia, Receptor Cross-Talk, Expresión Génica, Iniciación de la Cadena Peptídica Traduccional
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Predicting pathway cross-talks in ankylosing spondylitis through investigating the interactions among pathways

Gu, Xiang; Liu, Cong-Jian; Wei, Jian-Jie.
Braz. j. med. biol. res; 51 (1), 2018
Given that the pathogenesis of ankylosing spondylitis (AS) remains unclear, the aim of this study was to detect the potentially functional pathway cross-talk in AS to further reveal the pathogenesis of this disease. Using microarray profile of AS and biological pathways as study objects, Monte Carlo cros...
Área Bajo la Curva, Bases de Datos Genéticas, Perfilación de la Expresión Génica/métodos, Expresión Génica, Estudios de Asociación Genética, Análisis por Micromatrices/métodos, Método de Montecarlo, Receptor Cross-Talk/fisiología, Valores de Referencia, Transducción de Señal/genética, Espondilitis Anquilosante/genética
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