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Toll-like receptor 9 polymorphisms in brazilian patients with systemic lupus erythematosus: a pilot study

Barbosa, L M; Santiago, M B; Moretto, V T; Athanazio, D; Takahashi, D; Reis, E G; Lopes, M; Lemaire, D; Reis, M G.
Braz. j. biol; 83 (), 2023
Abstract Toll-like receptor 9 (TLR9) is an important component of the innate immune system and have been associated with several autoimmune diseases, such as Systemic Lupus Erythematosus (SLE). The aim of this study was to investigate polymorphisms in TLR9 gene in a Brazilian SLE patients group and their...
Brasil, Frecuencia de los Genes/genética, Predisposición Genética a la Enfermedad/genética, Lupus Eritematoso Sistémico/genética, Proyectos Piloto, Receptor Toll-Like 9/genética
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A meta-analysis of TLR4 and TLR9 SNPs implicated in severe malaria

Dhangadamajhi, Gunanidhi; Kar, Avishek; Rout, Ronnaly; Dhangadamajhi, Prabin.
Rev. Soc. Bras. Med. Trop; 50 (2), 2017
Abstract Toll-like receptors (TLRs) are critical mediators of the inflammatory response to malarial infection, and gene polymorphisms affecting TLR function may be partially responsible for inter-individual variation in disease manifestation. However, there are inconsistencies in the associations of comm...
Predisposición Genética a la Enfermedad/genética, Genotipo, Malaria Falciparum/genética, Polimorfismo de Nucleótido Simple, Factores de Riesgo, Índice de Severidad de la Enfermedad, Receptor Toll-Like 4/genética, Receptor Toll-Like 9/genética
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