Results: 2

La inhibición de los puntos de control inmunológico, una terapia en evolución: remembranza del Premio Nobel de Medicina 2018

Cárdenas-Oyarzo, Areli M; Bocchieri-Oyarce, Pamela A; Méndez-Laport, Cristian R; Zolezzi, Juan M; Ríos, Juvenal A.

Rev. méd. Chile; 150 (1), 2022

Professors James P. Allison and Tasuku Honjo were awarded with the 2018 Nobel Prize in Medicine for their contributions in cancer immunotherapy. The latter is a breakthrough in cancer therapy, aimed to overcome tumor-induced immunosuppression, leading to the reactivation of the immune system against canc...

Inhibidores de Puntos de Control Inmunológico, Neoplasias/tratamiento farmacológico, Antígeno CTLA-4/uso terapéutico, Inmunoterapia, Premio Nobel, Receptor de Muerte Celular Programada 1/uso terapéutico

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PD-1 blockade as a future treatment for colorectal cancer with microsatellite instability

Russo, Diana Maria Leite da Cunha; Barbosa, Laura Elisabete Ribeiro.

J. coloproctol. (Rio J., Impr.); 40 (4), 2020

ABSTRACT Introduction: Colorectal cancer is the third most common cancer worldwide, with about 15% of these tumours related with microsatellite instability, which confers distinct characteristics to these tumours, both clinicopathological and in the response to treatments. In fact, the poor response to ...

Neoplasias Colorrectales/patología, Inmunoterapia/métodos, Receptor de Muerte Celular Programada 1/uso terapéutico, Inestabilidad de Microsatélites

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