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Immunoexpression of TS, p53, COX2, EGFR, MSH6 and MLH1 biomarkers and its correlation with degree of differentiation, tumor staging and prognostic factors in colorectal adenocarcinoma: a retrospective longitudinal study

Batista, Wilson Roberto; Santos, Gianni; Vital, Flávia Maria Ribeiro; Matos, Delcio.
Säo Paulo med. j; 137 (1), 2019
ABSTRACT BACKGROUND: There are cases of colorectal tumors that, although small, show more aggressive evolution than large tumors. This motivated us to study whether there are any proteins capable of alerting about these changes. The aim here was to correlate the immunoexpression of the TS, p53, COX2, E...
Adenocarcinoma/mortalidad, Adenocarcinoma/patología, Biomarcadores de Tumor/análisis, Neoplasias Colorrectales/mortalidad, Neoplasias Colorrectales/patología, Ciclooxigenasa 2/análisis, Proteínas de Unión al ADN/análisis, Receptores ErbB/análisis, Inmunohistoquímica, Estimación de Kaplan-Meier, Estudios Longitudinales, Homólogo 1 de la Proteína MutL/análisis, Estadificación de Neoplasias, Modelos de Riesgos Proporcionales, Valores de Referencia, Estudios Retrospectivos, Timidilato Sintasa/análisis, Análisis de Matrices Tisulares, Proteína p53 Supresora de Tumor/análisis
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Prognostic utility of epidermal growth factor receptor (EGFR) expression in prostatic acinar adenocarcinoma

Hashmi, Atif Ali; Hashmi, Shumaila Kanwal; Irfan, Muhammad; Asif, Huda; Nisar, Laila; Naeem, Maheen; Khan, Erum Yousuf; Baloch, Samina; Faridi, Naveen.
Appl. cancer res; 39 (), 2019
Background: Epidermal growth factor receptor (EGFR) is potential prognostic biomarker expressed in many human cancers. Prognostic significance of EGFR immunohistochemical expression has not been established in prostatic acinar adenocarcinoma, therefore we aimed to evaluate the frequency of expression of ...
Receptores ErbB/análisis, Carcinoma de Células Acinares/patología, Neoplasias de la Próstata/patología, Pronóstico, Clasificación del Tumor, Carcinoma de Células Acinares/diagnóstico, Neoplasias de la Próstata/diagnóstico, Carcinoma de Células Acinares/genética, Neoplasias de la Próstata/genética, Biomarcadores de Tumor, Supervivencia sin Enfermedad
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Expression of epidermal growth factor receptor (EGFR) in cholangiocarcinomas: predictive factors and survival

GOMES, RODRIGO VIEIRA; RODRIGUES, MICHELE ÂNGELA; RODRIGUES, JOÃO BERNARDO SANCIO ROCHA; VIDIGAL, PAULA TEIXEIRA; DAMASCENO, KARINE ARAÚJO; LIMA, HENRIQUE ARAÚJO; GOMES, DAWIDSON ASSIS; MACHADO, CARLA JORGE; RESENDE, VIVIAN.
Rev. Col. Bras. Cir; 45 (3), 2018
ABSTRACT Objective: to evaluate the expression of the epithelial growth factor receptor (EGFR) by immunohistochemistry, and to verify its association with prognostic factors and survival of patients operated by cholangiocarcinoma. Methods: we verified the immunohistochemical expression of EGFR in 35 su...
Neoplasias de los Conductos Biliares/mortalidad, Neoplasias de los Conductos Biliares/patología, Colangiocarcinoma/mortalidad, Colangiocarcinoma/patología, Receptores ErbB/análisis, Inmunohistoquímica, Estimación de Kaplan-Meier, Persona de Mediana Edad, Pronóstico, Valores de Referencia, Distribución por Sexo, Coloración y Etiquetado
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