Novelty in improvement of CAR T cell-based immunotherapy with the aid of CRISPR system
Hematol., Transfus. Cell Ther. (Impr.); 46 (1), 2024
Abstract Introduction Chimeric Antigen Receptor (CAR) T cells have tremendous potentials for cancer treatment; however, various challenges impede their universal use. These restrictions include the poor function of T cells in tumor microenvironments, the shortage of tumor-specific antigens and, finally,...