Results: 32

Progestinas y cáncer de mama en terapia de reemplazo hormonal: cómo actúan y qué alternativas son más seguras

En algunos estudios se ha asociado a la terapia de reemplazo hormonal (TRH) con estrógenos y progestinas a un mayor riesgo de cáncer de mama que la terapia con estrógenos solos. Sin embargo, dependiendo de su naturaleza algunas progestinas serían más seguras que otras. Se buscaron y analizaron artí...

Different levels of adherence to the Mediterranean diet that do not change the risk of breast cancer in western women

Rev. chil. nutr; 49 (6), 2022
Breast cancer (BC) is the most common neoplasm in women globally. Healthy eating, a characteristic of the Mediterranean diet (MD), has been associated with a lower risk of developing BC, although this relationship remains inconclusive. This study aimed to analyse the relationship between MD adherence and...

Establishment and comparison of two methods to produce a rat model of mammary gland hyperplasia with hyperprolactinemia

Abstract This study aimed to establish and compare models of mammary gland hyperplasia (MGH) with hyperprolactinemia (HPRL) using two different methods. The models provide information on the relationship between mammary gland hyperplasia and associated hormones. Model A was constructed using intramuscula...

Integrated optical density analysis of the immunohistochemical expression of the progesterone receptor in the uterine endometrium of prepubertal araucana sheep

Int. j. morphol; 39 (5), 2021
SUMMARY: Progesterone receptors are expressed in the reproductive organs of adult sheep, where they regulate morphofunctional and reproductive development. However, various studies have shown the presence of these receptors in the uterus of prepubertal females. It is not clear what role these receptors h...

Evaluation of progesterone receptor expression in low- and high-grade astrocytomas

SUMMARY OBJECTIVE: Gliomas are tumors originating from glial cells. Gliomas are the most common primary neoplasms of the central nervous system, with astrocytomas being the most prevalent glioma subtype. Progesterone regulates several reproductive processes, such as ovulation and sexual behavior, and in...

Rol del receptor de progesterona como factor pronóstico de recidiva en cáncer de mama

Rev. argent. mastología; 40 (145), 2021
Introducción: las pacientes con cáncer de mama con receptores hormonales positivos mantienen una tasa de recurrencia significativa durante el seguimiento prolongado. La predicción del patrón de recurrencia puede ayudar en el desarrollo de estrategias específicas de vigilancia y tratamiento en pacien...

Cáncer de mama localmente avanzado. Neoadyuvancia: indicaciones y seguimiento

Rev. argent. mastología; 40 (145), 2021
El cáncer de mama localmente avanzado (CMLA) se manifiesta con grandes tumores (T3-4) y/o gran carga adenopática (N 1-2-3), sin metástasis a distancia e incluye estadios clínicos: II b, III a, III b y III c. La quimioterapia neoadyuvante (QTNA) es el tratamiento inicial para gran parte de las pacient...

Immunohistochemical and clinicopathologic features of estrogen receptor-negative, progesterone receptor-positive, HER-2 negative breast carcinomas

SUMMARY OBJECTIVE: Currently, there is an ongoing debate whether progesterone receptor positive and estrogen receptor negative breast carcinomas represent a true distinct subtype of tumor or a mere immunohistochemical artifact. In this study, we conducted an immunohistochemistry panel with the antibodie...

Comparação entre expressão de receptores hormonais e de HER-2 entre células tumorais circulantes e metástases de câncer de mama

Introdução: O câncer de mama é a neoplasia mais comum em mulheres. A maioria deles é diagnosticada em estágios iniciais, quando o tratamento visa a cura. Mas apesar dos avanços no tratamento, metástases à distância podem ocorrer. A biópsia das lesões metastáticas é recomendada para confirma...

Survival rates of advanced estrogen-receptor positive breast cancer. Analysis of 211 cases

Rev. méd. Chile; 148 (9), 2020
ABSTRACT Background: About 80% of breast cancer (BC) cases express estrogen receptor (ER), which has been correlated with good prognosis and response to estrogen deprivation Aim: To characterize ER positive advanced BC (ABC) patients treated at our institution assessing the impact of clinical pre-sentati...