Results: 6

Time-dependent proregenerative effects of exogenous melatonin on the transected sciatic nerve

Int. j. morphol; 41 (1), 2023
SUMMARY: Microsurgical procedures are the treatment of choice of peripheral nerve injuries, but often fail to reach full functional recovery. Melatonin has neuroprotective actions and might be used as a possible proregenerative pharmacological support. Therefore, the aim of this study was to analyze the ...

Effect of Tacrolimus and Cyclosporine Immunosuppressants on Peripheral Nerve Regeneration: Systematic Review and Meta-analysis

Abstract Peripheral nerve damage is an important cause of seeking medical attention. It occurs when the continuity of structures is interrupted and the propagation of nervous impulses is blocked, affecting the functional capacity of individuals. To assess the effects of the immunosuppressants tacrolimus ...

Serotonin induces or inhibits neuritic regeneration of leech CNS neurons depending on neuronal identity

Braz. j. med. biol. res; 52 (2), 2019
Recovery of motor function after central nervous system (CNS) injury is dependent on the regeneration capacity of the nervous system, which is a multifactorial process influenced, among other things, by the role of neuromodulators such as serotonin. The neurotransmitter serotonin can promote neuronal reg...

Effects of ozone therapy on facial nerve regeneration

Abstract Introduction: Ozone may promote moderate oxidative stress, which increases antioxidant endogenous systems. There are a number of antioxidants that have been investigated therapeutically for improving peripheral nerve regeneration. However, no previous studies have reported the effect of ozone t...

Effect of ozone and methylprednisolone treatment following crush type sciatic nerve injury

Acta cir. bras; 31 (11), 2016
ABSTRACT PURPOSE: To assess and compare the histopathological effects of ozone therapy and/or methylprednisolone (MPS) treatment on regeneration after crush type sciatic nerve injury. METHODS: Forty Sprague-Dawley male rats were randomly allocated into four groups. Four groups received the following r...

Señalización de la angiotensina II, a través de la producción de radicales libres en estructuras del sistema nervioso: papel en el estres agudo y crónico

Existen evidencias que apoyan la participación de las especies reactivas de oxígeno en las cascadas de señalización y transducción intracelular de la angiotensina II. La ANG II es importante en el mantenimiento de la homeostasis corporal, regulando la presión ar...