SUMMARY: Microsurgical procedures are the treatment of choice of peripheral nerve injuries, but often fail to reach full functional recovery. Melatonin has neuroprotective actions and might be used as a possible proregenerative pharmacological support. Therefore, the aim of this study was to analyze the ...
Abstract Purpose To investigate the effects of Chemically Extracted Acellular Nerves (CEANs) when combined with Adipose-Derived mesenchymal Stem Cell (ADSC) transplantation on the repair of sciatic nerve defects in rabbits. Methods A total of 71 six-month-old Japanese rabbit were used in this study. ...
Fenómenos Biomecánicos,
Electromiografía,
Trasplante de Células Madre Mesenquimatosas/métodos,
Células Madre Mesenquimatosas,
Regeneración Nerviosa/fisiología,
Tejido Nervioso/cirugía,
Tejido Nervioso/trasplante,
Conejos,
Valores de Referencia,
Reproducibilidad de los Resultados,
Nervio Ciático/fisiopatología,
Nervio Ciático/cirugía,
Neuropatía Ciática/fisiopatología,
Neuropatía Ciática/cirugía,
Resultado del Tratamiento
ABSTRACT Growth hormone (GH) is best known for its effect stimulating tissue and somatic growth through the regulation of cell division, regeneration and proliferation. However, GH-responsive neurons are spread over the entire central nervous system, suggesting that they have important roles in the brain...
SUMMARY: The aim of this study was to determine the possible regenerative effect of neuroectodermal stem cells on the ultrastructural, and locomotor function resulting from compressed injury to the spinal cord in a rat model. Forty male rats were divided into control and sham groups (20 rats each). Compr...
Abstract Purpose: To evaluate three different kinds of neurorrhaphy of the peroneal nerve. Methods: Eigthy rats were divided into 5 groups. Control: nerve had no intervention. End-to-end (EE): nerve was cut and elongated with a nerve graft with two end-to-end neurorrhaphies. End-to-side (ES): nerve w...
ABSTRACT Objective To establish the correlation between clinical evaluation of motor function recovery and daily living activities in 30 patients with upper traumatic brachial plexus injury submitted to surgery. Methods The score of the Disabilities of the Arm, Shoulder and Hand (DASH) questionnaire ...
Roque, José Sidney;
Pomini, Karina Torres;
Buchaim, Rogério Leone;
Buchaim, Daniela Vieira;
Andreo, Jesus Carlos;
Roque, Domingos Donizeti;
Rodrigues, Antonio de Castro;
Rosa Júnior, Geraldo Marco;
Moraes, Luis Henrique Rapucci;
Viterbo, Fausto.
Abstract Purpose: To evaluated the tubulization technique with standard and inside-out vein, filled or not with platelet-rich plasma (PRP), in sciatic nerve repair. Methods: Seventy male Wistar rats were randomly divided into five groups: IOVNF (Inside-Out Vein with No Filling); IOVPRP (Inside-Out Ve...
Regeneración Tisular Dirigida/métodos,
Venas Yugulares/trasplante,
Vaina de Mielina/fisiología,
Regeneración Nerviosa/fisiología,
Plasma Rico en Plaquetas,
Nervio Ciático/cirugía,
Modelos Animales de Enfermedad,
Fibras Nerviosas,
Traumatismos de los Nervios Periféricos/cirugía,
Distribución Aleatoria,
Ratas Wistar,
Valores de Referencia,
Reproducibilidad de los Resultados,
Nervio Ciático/lesiones,
Trasplante Autólogo/métodos,
Resultado del Tratamiento
Abstract Purpose: To compare the functional result of standart vein grafts and inside-out vein graft technique on sciatic nerve repair. Methods: We used 24 male Wistar rats divided into 4 groups: control group (CG), standard vein graft group (SVG), Inside-out vein graft group (IOVG) and denervated Gro...
As moléculas de adesão celular vem sendo utilizadas na coaptação de nervos lesados como alternativa a consagrada neurorrafia, entretanto, faltam estudos experimentais definitivos em relação às duas técnicas. O objetivo deste estudo foi avaliar a recuperação funcional do nervo ciático reparado ...
