Prognostic significance of bi/oligoclonality in childhood acute lymphoblastic leukemia as determined by polymerase chain reaction
Säo Paulo med. j; 119 (5), 2001
CONTEXT: The CDR-3 region of heavy-chain immunoglobulin has been used as a clonal marker in the study of minimal residual disease in children with acute lymphoblastic leukemia. Southern blot and polymerase chain reaction studies have demonstrated the occurrence of bi/oligoclonality in a variable number o...
Linfoma de Burkitt, Reacción en Cadena de la Polimerasa, Linfoma de Burkitt, Estudios Prospectivos, Estudios de Seguimiento, Cadenas Pesadas de Inmunoglobulina, Regiones Determinantes de Complementariedad, Línea Celular, Células Clonales, Recurrencia, Supervivencia sin Enfermedad, Factores de Riesgo