Grandisin induces apoptosis in leukemic K562 cells
Braz. J. Pharm. Sci. (Online); 53 (1), 2017
Abstract In this study, the potential antileukemic activity of grandisin, a lignan extracted from Piper solmsianum, was evaluated against the leukemic line K562. The cytotoxicity of grandisin (0.018 to 2.365 µM) was evaluated in K562 and normal peripheral blood lymphocytes by Trypan Blue Exclusion and M...