Chloride and sodium ion concentrations in saliva and sweat as a method to diagnose cystic fibrosis
J. pediatr. (Rio J.); 95 (4), 2019
Abstract Objective: Cystic fibrosis diagnosis is dependent on the chloride ion concentration in the sweat test (≥ 60 mEq/mL - recognized as the gold standard indicator for cystic fibrosis diagnosis). Moreover, the salivary glands express the CFTR protein in the same manner as sweat glands. Given t...
Biomarcadores/análisis, Estudios de Casos y Controles, Cloruros/análisis, Fibrosis Quística/diagnóstico, Fibrosis Quística/genética, Regulador de Conductancia de Transmembrana de Fibrosis Quística/análisis, Regulador de Conductancia de Transmembrana de Fibrosis Quística/genética, Genotipo, Saliva/química, Sodio/química, Sodio/metabolismo, Sudor/química