LILACS – Literatura Latinoamericana y del Caribe de Ciencias de la Salud

RP-HPLC method development and validation for estimation of rivaroxaban in pharmaceutical dosage forms

Çelebier, Mustafa; Reçber, Tuba; Koçak, Engin; Altinöz, Sacide.

Braz. j. pharm. sci; 49 (2), 2013

Rivaroxaban, an anti-clotting medication, acts at a crucial point in the blood-clotting process and stops the formation of blood clots. In this study, RP-HPLC method was developed for the determination of rivaroxaban in tablets (Xarelto® (10 mg)). Phenomenex Luna 5 µm C18 100 Å LC Column (250 x 4.6 mm...

Cromatografía Líquida de Alta Presión/métodos, Estudio de Validación, Rivaroxabán/farmacocinética, Indicadores (Estadística), Formas de Dosificación/normas

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New perspectives and recommendations for anticoagulant therapy post orthopedic surgery

Anticoagulant therapy is essential for the prevention of risks associated with the formation of thrombus in patients after surgery, especially in orthopedics. Recently, new oral anticoagulants were introduced in the therapeutic arsenal. This fact is important, because the current drug of choice in clinic...