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DNA damage as a potential marker in the clinical follow-up of female patients with treated cancer

Pupo-Balboa, Judith Beatriz; Robaina-Castellanos, Martha Sonia; Gutiérrez-Gutiérrez, Reinaldo; Pandolfi-Blanco, Anamarys; Fariñas-Rodríguez, Lucía.
Rev. colomb. cancerol; 25 (1), 2021
Abstract Objective: To identify individual differences in the basal damage (DB) of peripheral leukocyte DNA from women with cancer in remission. Methods: Cross-sectional analytical study in which 24 women with cancer in remission from different locations and 24 supposedly healthy women participated. Th...
Daño del ADN, Derivación y Consulta, Mujeres, Roturas del ADN de Doble Cadena, Roturas del ADN, Terapéutica, Métodos
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Mycobacterium tuberculosis promotes genomic instability in macrophages

Castro-Garza, Jorge; Luévano-Martínez, Miriam Lorena; Villarreal-Treviño, Licet; Gosálvez, Jaime; Fernández, José Luis; Dávila-Rodríguez, Martha Imelda; García-Vielma, Catalina; González-Hernández, Silvia; Cortés-Gutiérrez, Elva Irene.
Mem. Inst. Oswaldo Cruz; 113 (3), 2018
BACKGROUND Mycobacterium tuberculosis is an intracellular pathogen, which may either block cellular defensive mechanisms and survive inside the host cell or induce cell death. Several studies are still exploring the mechanisms involved in these processes. OBJECTIVES To evaluate the genomic instability o...
Inestabilidad Genómica/genética, Daño del ADN, Roturas del ADN, Mycobacterium tuberculosis/fisiología, Hibridación Fluorescente in Situ
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