LILACS – Literatura Latinoamericana y del Caribe de Ciencias de la Salud

Evaluation of Polymorphisms in IL8 and IL16 Genes in Patients with Acute Coronary Syndrome

Silva, Lílian Caroliny Amorim; Araújo, Romário Martins; Soares, Fábia Carla Silva; Werkhauser, Roberto Pereira; Montenegro, Sergio Tavares; Tashiro, Tetsuo; Carvalho, Viviane do Carmo Vasconcelos; Montenegro, Silvia Maria Lucena.

Int. j. cardiovasc. sci. (Impr.); 33 (3), 2020

Abstract Background: Acute coronary syndrome (ACS) is a cardiovascular disease caused by obstruction of coronary arteries by atheromatous plaque. Susceptibility to this disease may be related to genetic variations, such as single nucleotide polymorphisms (SNPs). Objective: In this study, we evaluated t...

Polimorfismo de Nucleótido Simple/genética, Genotipo, Síndrome Coronario Agudo/genética, Interleucina-16, Interleucina-8, Placa Aterosclerótica, Tabaquismo, Diabetes Mellitus, Dislipidemias

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The branched-chain amino acid transaminase 1 -23c/g polymorphism confers protection against acute coronary syndrome

Ramírez-Bello, Julian; Vargas-Alarcón, Gilberto; Pérez-Méndez, Óscar; Martínez-Ríos, Marco A.; Peña-Duque, Marco A.; Cardoso-Saldaña, Guillermo; Posadas-Romero, Carlos; Sierra-Martínez, Mónica; Fragoso, José M..

Rev. invest. clín; 72 (1), 2020

ABSTRACT Background: Previous studies have shown an association between polymorphisms of the BAT1-NF-κB inhibitor-like-1 (NFKBIL1)-LTA genomic region and susceptibility to myocardial infarction and acute coronary syndrome (ACS). Objective: The objective of the study was to study the role of three ...

Síndrome Coronario Agudo/genética, Proteínas Adaptadoras Transductoras de Señales/genética, Estudios de Casos y Controles, ARN Helicasas DEAD-box/genética, Frecuencia de los Genes, Predisposición Genética a la Enfermedad, Genotipo, Linfotoxina-alfa/genética, México, Infarto del Miocardio/genética, Polimorfismo de Nucleótido Simple

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Gene mutations of platelet glycoproteins and response to tirofiban in acute coronary syndrome

Mansur, Antonio de Padua; Roggerio, Alessandra; Takada, Júlio Yoshio; Caribé, Pérola Michelle Vasconcelos; Avakian, Solange Desirée; Strunz, Célia Maria Cassaro.

Säo Paulo med. j; 134 (3), 2016

CONTEXT AND OBJECTIVES: Glycoprotein inhibitors (abciximab, eptifibatide and tirofiban) are used in patients with unstable angina and non-ST-segment elevation myocardial infarction before percutaneous coronary intervention. Of these, tirofiban is the least effective. We hypothesized that the response to...

Abciximab, Síndrome Coronario Agudo/tratamiento farmacológico, Síndrome Coronario Agudo/genética, Angina Inestable/tratamiento farmacológico, Angina Inestable/genética, Anticuerpos Monoclonales/uso terapéutico, Eptifibatida, Genotipo, Fragmentos Fab de Inmunoglobulinas/uso terapéutico, Mutación, Péptidos/uso terapéutico, Agregación Plaquetaria/efectos de los fármacos, Agregación Plaquetaria/genética, Inhibidores de Agregación Plaquetaria/uso terapéutico, Complejo GPIIb-IIIa de Glicoproteína Plaquetaria/antagonistas & inhibidores, Complejo GPIIb-IIIa de Glicoproteína Plaquetaria/genética, Glicoproteínas de Membrana Plaquetaria/genética, Reacción en Cadena de la Polimerasa, Estudios Prospectivos, Tirofibán, Tirosina/análogos & derivados, Tirosina/uso terapéutico

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