LILACS – Literatura Latinoamericana y del Caribe de Ciencias de la Salud

Síndrome hemolítico urémico asociado a toxina Shiga con hipocomplementemia en edad atípica. Caso clínico

Cathalifaud, Daniel; Sandoval, Javier; Cerda, Tomás; Reyes, Diego; Sepúlveda, Rodrigo A.

Rev. méd. Chile; 149 (11), 2021

The Shiga toxin associated (Stx) hemolytic uremic syndrome (HUS) is an important cause of acute renal failure (ARF) and the most common cause of thrombotic microangiopathy (TMA) in pediatrics. Primary atypical HUS (aHUS) is a rare disease due to a genetic defect in the alternative complement pathway. Bot...

Lesión Renal Aguda/etiología, Síndrome Hemolítico Urémico Atípico/complicaciones, Síndrome Hemolítico Urémico Atípico/diagnóstico, Diarrea/complicaciones, Enfermedades del Sistema Inmune, Pronóstico, Toxina Shiga

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Nephrotic syndrome associated with primary atypical hemolytic uremic syndrome

Abstract Primary atypical hemolytic-uremic syndrome is a rare disease characterized by non-immune microangiopathic hemolytic anemia, thrombocytopenia, and renal dysfunction; it is related to alterations in the regulation of the alternative pathway of complement due to genetic mutations. The association w...