SUMMARY We report a rare case of Cushing's syndrome in a 37-year-old female who initially presented with localized acinic cell carcinoma of the parotid gland. In January 2014, she underwent a right parotidectomy with facial nerve preservation and adjuvant radiotherapy. In August 2018, she presented a his...
SUMMARY Cyclic Cushing's syndrome (CS) due to thymic carcinoid is a rare disorder. We report a case of cyclic CS due to ectopic adrenocorticotropic hormone (ACTH)-secreting atypical thymic carcinoid tumor and reviewed similar cases published in the literature. Our patient had hypercortisolemia lasting ap...
Resumen: Identificar la causa de un síndrome de Cushing dependiente de adrenocorticotropina (ACTH) es esencial para realizar un tratamiento correcto. La hipersecreción de ACTH es debida en su mayoría a un tumor hipofisario (enfermedad de Cushing) o, en un 10%-20%, a tumores con producción ectópica d...
ABSTRACT Objective The aim was to describe the clinical features of patients with ectopic Cushing syndrome (ECS) from Colombia and compare these findings with other series to provide the best management for these patients. Materials and methods Records of patients with ECS from 1986 to 2017 were retr...
We report a previously healthy 34-year-old woman, presenting with a seven-month history of arterial hypertension, amenorrhea, weight gain, facial edema, acne, hirsutism and low back pain. A CT scan showed a right adrenal mass of 18 × 13 × 12.5 cm, and multiple vertebral and rib fractures. The hormonal ...
RESUMO Objetivo: Analisar as características clínicas, laboratoriais e histopatológicas e o percurso até o estabelecimento do diagnóstico e do tratamento de pacientes com carcinoma de suprarrenal (CSR). Métodos: Estudo retrospectivo com 13 pacientes tratados no serviço de oncologia pediátrica...
Neoplasias de las Glándulas Suprarrenales/mortalidad,
Neoplasias de las Glándulas Suprarrenales/patología,
Neoplasias de las Glándulas Suprarrenales/terapia,
Glándulas Suprarrenales/patología,
Adrenalectomía/métodos,
Adrenalectomía/estadística & datos numéricos,
Antineoplásicos/uso terapéutico,
Brasil/epidemiología,
Carcinoma/mortalidad,
Carcinoma/patología,
Carcinoma/terapia,
Síndrome de Cushing/diagnóstico,
Síndrome de Cushing/etiología,
Detección Precoz del Cáncer,
Estadificación de Neoplasias,
Evaluación de Procesos y Resultados en Atención de Salud,
Estudios Retrospectivos,
Tiempo de Tratamiento/estadística & datos numéricos
SUMMARY Ectopic adrenocorticotropic hormone (ACTH) syndrome is characterized by hypercortisolism due to the hypersecretion of a non-pituitary ACTH-secreting tumor leading to Cushing's syndrome. Only a few cases have been reported previously as causing ectopic ACTH related to paraganglioma. Herein, we pre...
Síndrome de ACTH Ectópico/etiología,
Síndrome de ACTH Ectópico/patología,
Síndrome de Cushing/etiología,
Síndrome de Cushing/patología,
Inmunohistoquímica,
Neoplasias Renales/complicaciones,
Neoplasias Renales/metabolismo,
Neoplasias Renales/patología,
Metástasis Linfática,
Paraganglioma/complicaciones,
Paraganglioma/metabolismo,
Paraganglioma/patología,
Hipófisis/patología,
Tomografía Computarizada por Tomografía de Emisión de Positrones
Machado, Márcio Carlos;
Fragoso, Maria Candida Barisson Vilares;
Moreira, Ayrton Custódio;
Boguszewski, César Luiz;
Vieira Neto, Leonardo;
Naves, Luciana A;
Vilar, Lucio;
Araújo, Luiz Antônio de;
Czepielewski, Mauro A;
Gadelha, Monica R;
Musolino, Nina Rosa Castro;
Miranda, Paulo Augusto C;
Bronstein, Marcello Delano;
Ribeiro-Oliveira Jr, Antônio.
ABSTRACT Although it is a rare condition, the accurate diagnosis and treatment of Cushing’s disease is important due to its higher morbidity and mortality compared to the general population, which is attributed to cardiovascular diseases, diabetes mellitus and infections. Screening for hypercortiso...
Adenoma Hipofisario Secretor de ACTH/complicaciones,
Adenoma Hipofisario Secretor de ACTH/diagnóstico,
Adenoma/complicaciones,
Adenoma/diagnóstico,
Brasil,
Cromatografía Líquida de Alta Presión,
Consenso,
Síndrome de Cushing/diagnóstico,
Síndrome de Cushing/etiología,
Dexametasona,
Diagnóstico Diferencial,
Glucocorticoides,
Hidrocortisona/sangre,
Imagen por Resonancia Magnética
Medullary thyroid carcinoma (MTC) may rarely present with paraneoplastic syndromes. Among the most frequent ones are the appearance of diarrhea and ectopic Cushing syndrome (ECS). The ECS in the context of MTC is usually present in patients with distant metastatic disease. The use of drugs such as ketoco...
Carcinoma Neuroendocrino/complicaciones,
Carcinoma Neuroendocrino/tratamiento farmacológico,
Síndrome de Cushing/tratamiento farmacológico,
Síndrome de Cushing/etiología,
Progresión de la Enfermedad,
Estadificación de Neoplasias,
Piperidinas/uso terapéutico,
Quinazolinas/uso terapéutico,
Neoplasias de la Tiroides/complicaciones,
Neoplasias de la Tiroides/tratamiento farmacológico,
Resultado del Tratamiento
