Novel identification and characterisation of Transient receptor potential melastatin 3 ion channels on Natural Killer cells and B lymphocytes: effects on cell signalling in Chronic fatigue syndrome/Myalgic encephalomyelitis patients
Biol. Res; 49 (), 2016
BACKGROUND: Transient receptor potential melastatin 3 (TRPM3) cation channels are ubiquitously expressed by multiple cells and have an important regulatory role in calcium-dependent cell signalling to help maintain cellular homeostasis. TRPM3 protein expression has yet to be determined on Natural Killer ...
Linfocitos B/metabolismo, Síndrome de Fatiga Crónica/sangre, Células Asesinas Naturales/metabolismo, Canales Catiónicos TRPM/metabolismo, Canales de Calcio/sangre, Inhibidores Enzimáticos/uso terapéutico, Síndrome de Fatiga Crónica/tratamiento farmacológico, Citometría de Flujo/métodos, Inmunofenotipificación/métodos, Tapsigargina/uso terapéutico, Análisis de Varianza, Estudios de Casos y Controles, Valores de Referencia