LILACS – Literatura Latinoamericana y del Caribe de Ciencias de la Salud

Investigation of anti-Alzheimer’s activity of aqueous extract of areca nuts (Areca catechu L): in vitro and in vivo studies

Bozorgi, Mahboubeh; Najafi, Zahra; Omidpanah, Sahar; Sadri, Arash; Narimani, Zahra; Moghadam, Farshad Homayouni; Edraki, Najmeh; Akbarzadeh, Tahmineh; Saeedi, Mina.

Bol. latinoam. Caribe plantas med. aromát; 20 (4), 2021

Alzheimer’s disease (AD) is an age-related neurodegenerative disorder. Sever cognitive and memory impairments, huge increase in the prevalence of the disease, and lacking definite cure have absorbed worldwide efforts to develop therapeutic approaches. Since many drugs have failed in the clinical tria...

Enfermedad de Alzheimer/prevención & control, Enfermedad de Alzheimer/tratamiento farmacológico, Extractos Vegetales/administración & dosificación, Areca/química, Medicina Tradicional, Péptidos beta-Amiloides/efectos de los fármacos, beta-Amilasa/antagonistas & inhibidores, Ácido Aspártico Endopeptidasas/efectos de los fármacos, Ácido Aspártico Endopeptidasas/antagonistas & inhibidores, Secretasas de la Proteína Precursora del Amiloide/efectos de los fármacos, Secretasas de la Proteína Precursora del Amiloide/antagonistas & inhibidores, Prueba del Laberinto Acuático de Morris, Enfermedad de Alzheimer/enzimología, Fármacos Neuroprotectores

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Caracterização da inter-relação entre as vias de sinalização Notch e TLR na paracoccidioidomicose experimental

Romera, Lavínia Maria Dal'Mas.

A paracoccidioidomicose é uma micose sistêmica de natureza profunda que afeta preferencialmente o tecido pulmonar podendo disseminar via linfo-hematogênica para outros órgãos e tecidos, sendo causada principalmente pelo Paracoccidioides brasiliensis, fungo que apresenta dimorfismo térmico. O sistem...

34921, Receptor Toll-Like 4/clasificación, Micosis/prevención & control, Paracoccidioidomicosis/complicaciones, Macrófagos, Paracoccidioides, Receptor Notch1/clasificación, Secretasas de la Proteína Precursora del Amiloide/administración & dosificación, 34921

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Neurobiological pathways to Alzheimers disease: Amyloid-beta, Tau protein or both?

Paula, Vanessa de Jesus R. de; Guimarães, Fabiana Meira; Diniz, Breno Satler; Forlenza, Orestes Vicente.

Dement. neuropsychol; 3 (3), 2009

Abstract: Alzheimers disease (AD) is a neurodegenerative disease characterized by progressive cognitive decline, including memory loss, behavioral and psychological symptoms and personality changes. The neuropathological hallmarks of AD are the presence of neuritic (senile) plaques (NP) and neurofibrilla...

Proteínas tau, Secretasas de la Proteína Precursora del Amiloide, Péptidos beta-Amiloides, Enfermedad de Alzheimer

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