Introducción. Durante el desarrollo de la pandemia por SARS-CoV-2 en Antioquia se presentaron picos epidemiológicos relacionados con las variantes α, ɣ, β, µ, ƛ y δ, donde δ tuvo la mayor incidencia y prevalencia. Este linaje se considera una variante de preocupación dadas las manifestaciones c...
Adlat, Salah;
Hayel, Farooq;
Yang, Ping;
Chen, Yang;
Mar Oo, Zin;
Zaw Myint, May Zun;
Kumar Sah, Rajiv;
Bahadar, Noor;
Al-Azab, Mahmoud;
Binta Bah, Fatoumata;
Zheng, Yaowu;
Feng, Xuechao.
BACKGROUND: Many human genetic diseases arise from point mutations. These genetic diseases can theoretically be corrected through gene therapy. However, gene therapy in clinical application is still far from mature. Nearly half of the pathogenic single-nucleotide polymorphisms (SNPs) are caused by G:C>A:...
BACKGROUND: Short Tandem repeats (STRs) existed as popular elements in both eukaryotic and prokaryotic genomes. RESULTS: In this study, we analyzed the characteristics, distributions, and motif features of STRs within whole-genomes of 140 plant species. The results showed that STR density was negatively ...
Hajrah, Nahid H;
Rabah, Samar O;
Alghamdi, Mohammed K;
Atef, Ahmed;
Edris, Sherif;
Alhebshi, Alawiah M;
Hassan, Sabah M;
Alzahrani, Dhafer A;
Bahieldin, Ahmed;
Mutwakil, Mohammed HZ;
Alqurashi, Yaser E;
Al-Zahrani, Hassan S;
Abo-Aba, Salah EM;
Jansen, Robert K;
Sabir, Jamal SM;
Hall, Neil;
Rasool Kamli, Majid.
BACKGROUND: Jasmonic acid (JA) is a signal transducer molecule that plays an important role in plant development and stress response; it can also efficiently stimulate secondary metabolism in plant cells. RESULTS: RNA-Seq technology was applied to identify differentially expressed genes and study the tim...
Abstract INTRODUCTION: This study evaluated the epidemiology of American cutaneous leishmaniasis in the immediate region of Ji-Paraná, Rondônia State. METHODS: Samples and epidemiological data were collected from 105 patients. RESULTS: Leishmania infection was observed in 58 (55.2%) patients, and ...
Current understanding of the genetic factors contributing to the etiology of non-syndromic craniosynostosis (NSC) remains scarce. The present work investigated the presence of variants in ALX4, EFNA4, and TWIST1 genes in children with NSC to verify if variants within these genes may contribute to the occ...
Cercopithifilaria bainae is a nematode belonging to the family Onchocercidae that parasitizes the subcutaneous tissue of dogs. Its transmission occurs through the tick Rhipicephalus sanguineus and its geographical distribution overlaps that of this vector. The present study reports the detection of micro...
OBJECTIVES: High incidence and case fatality of unstable angina (UA) is, to a large extent, a consequence of the lack of highly sensitive and specific non-invasive markers. Circulating microRNAs (miRNAs) have been widely recommended as potential biomarkers for numerous diseases. In the present study, we ...
A tuberculose (TB) resistente aos fármacos é um problema mundial. As mutações mais frequentes associadas à resistência à isoniazida em Mycobacterium tuberculosis ocorrem no códon 315 do gene katG, causando níveis moderados a altos de resistência, e na região promotora do gene inhA, associadas ...
Bacillus Calmette Guerin (BCG) vaccines comprise a family of related strains. Whole genome sequencing has allowed the better characterisation of the differences between many of the BCG vaccines. As sequencing technologies improve, updating of publicly available sequence data becomes common practice. We h...
