Results: 5

Disseminated intravascular coagulation phenotype is regulated by the TRPM7 channel during sepsis

Biol. Res; 56 (), 2023
BACKGROUND: Sepsis is an uncontrolled inflammatory response against a systemic infection that results in elevated mortality, mainly induced by bacterial products known as endotoxins, producing endotoxemia. Disseminated intravascular coagulation (DIC) is frequently observed in septic patients and is assoc...

Activated platelets in central venous catheters: a flow cytometry and numerical simulation approach

Acta sci., Health sci; 43 (), 2021
The central venous catheter that is inserted in patients undergoing hemodialysis can cause hemodynamic instability and trigger complications such as thrombus formation. The objective of this study was to investigate hemostatic and numerical influences on thrombus formation in patients underg...

Intercellular mediators in bone remodeling regulation in the experimental renal pathology

Actual. osteol; 15 (3), 2019
Bone metabolism disorders are characterized by an imbalance of bone resorption and formation in the bone remodeling process. Glucocorticoids that are used to treat kidney diseases exacerbate these disorders. P-selectin and galectin-3 are molecules involved in the sclerotic process in kidney, whereas bone...

Análise da expressão de citocinas e quimiocinas, dos agregados de plaquetas-leucócitos e dos mediadores solúveis sCD40L e sCD62P no melanoma cutâneo

Introdução: O melanoma cutâneo é uma neoplasia maligna dos melanócitos da pele com incidência variável no mundo e o prognóstico é desfavorável nos estágios mais avançados. O desenvolvimento do melanoma está associado ao sistema imunológico e a maior evolução no seu tratamento se deu a par...

Correlations of inhaled NO with the cTnI levels and the plasma clotting factor in rabbits with acute massive pulmonary embolism

Acta cir. bras; 33 (8), 2018
Abstract Purpose: To investigate the correlation of inhaled nitric oxide (NO) on plasma levels of cardiac troponin I (cTnI) and von Willebrand factor (vWF), glycoprotein (GP) IIb/IIIa, granule membrane protein 140 (GMP-140) in rabbits with acute massive pulmonary embolism (PE). Methods: Thirty apanese...