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Does Parkinson's disease start in the gut?

Arq. neuropsiquiatr; 76 (2), 2018
ABSTRACT Current understanding of the pathophysiology of Parkinson's disease suggests a key role of the accumulation of alpha-synuclein in the pathogenesis. This critical review highlights major landmarks, hypotheses and controversies about the origin and progression of synucleinopathy in Parkinson's dis...