SUMMARY: Resveratrol (RES) and quercetine (QRC), is a promising agent relevant for both cancer chemoprevention and treatment via several signaling pathways, involved in their anticancer activity related to its chemotherapeutic potential, associated with the induction of ROS generation in cancer cells, le...
This article aimed to discuss the protection of trans
-
nerolidol on vascular endothelial cells
(ECs) injured by lipopolysac
charides. ECs were divided into four groups: normal, model, low and high
dose trans
-
nerolidol treatment groups. The cell survival rate and th...
SUMMARY: Spinal cord injury (SCI) usually arises from compression due to traffic accidents and falls, resulting in varying degrees of movement, sensory loss, and possible paralysis. Glabridin (Gla) is a natural compound derived from licorice. It significantly affects drug development and medicine because...
To study the effect of 50% ethanol extract of
Bougainvillea xbuttiana
on the enzymatic
activity, cell via
bility and cytokine production provoked by the venom of
Bothrops jararaca
in macro
-
phages. Three assays were used to study the effects of
B. xbuttiana
extract on the dama...
Extractos Vegetales/farmacología,
Venenos de Crotálidos/antagonistas & inhibidores,
Macrófagos/efectos de los fármacos,
Nyctaginaceae/química,
Citocinas,
Ensayo de Inmunoadsorción Enzimática,
Etanol,
Fosfolipasas A2,
Ratones Endogámicos BALB C,
Venenos de Crotálidos/enzimología,
Supervivencia Celular/efectos de los fármacos
Cancer cells
modify lipid metabolism to proliferate,
Passiflora edulis
(
P. edulis
) fruit juice
(ZuFru) has antitumor activity, but whether a mechanism is through modulation of cell lipids is unknown.
T
o establish if ZuFru modifies cholesterol and triglycerides in SW480
and SW620...
Passiflora/química,
Extractos Vegetales/administración & dosificación,
Anticarcinógenos,
Jugos de Frutas y Vegetales/análisis,
Neoplasias Colorrectales/tratamiento farmacológico,
Proliferación Celular/efectos de los fármacos,
Colesterol,
Triglicéridos,
Línea Celular Tumoral/efectos de los fármacos,
Extractos Vegetales/química,
Fenoles/análisis,
Flavonoides/análisis,
Antioxidantes,
Supervivencia Celular/efectos de los fármacos,
Polisacáridos/análisis
Objective: This study aimed to evaluate stem cell from human deciduous teeth (SHED) viability after exposure to different bioceramic materials. Material and Methods: Discs were constructed to obtain the material extracts according to the following groups: G1 - Bio-C Repair, G2 - MTA Repair HP, G3 - Thera...
SUMMARY: To evaluate the anti-cancer effects of yeast extract on resistant cells, autophagy and necroptosis were investigated in 5-fluorouracil (5-FU)-resistant colorectal cancer cells. Further underlying characteristics on drug resistance were evaluated, focused on ERK-RSK-ABCG2 linkage. SNU-C5 and 5-FU...
Extractos Vegetales/farmacología,
Neoplasias Colorrectales/tratamiento farmacológico,
Resistencia a Antineoplásicos,
Fluorouracilo,
Autofagia,
Antineoplásicos/farmacología,
Proteínas Quinasas S6 Ribosómicas 90-kDa,
Transportador de Casetes de Unión a ATP, Subfamilia G, Miembro 2,
Células Tumorales Cultivadas,
Levaduras,
Necroptosis,
Supervivencia Celular/efectos de los fármacos,
Western Blotting,
Electroforesis
SUMMARY: Intervertebral disc degeneration (IVDD) is induced by nucleus pulposus (NP) dysfunction as a result of massive loss of NP cells. It has been reported that the acidic microenvironment of the intervertebral disc (IVD) can induce NP cell pyroptosis, and that up-regulation of periostin (POSTN) expre...
Ácidos/química,
Ambiente,
Degeneración del Disco Intervertebral,
Núcleo Pulposo/fisiopatología,
Moléculas de Adhesión Celular/metabolismo,
Núcleo Pulposo/citología,
Proteína con Dominio Pirina 3 de la Familia NLR,
Ratas Sprague-Dawley,
Moléculas de Adhesión Celular/genética,
Reacción en Cadena en Tiempo Real de la Polimerasa,
Western Blotting,
Ensayo de Inmunoadsorción Enzimática,
Supervivencia Celular,
d0123330
Pavón, Alequis;
Corsini, Gino;
Orellana, Paz;
Calisto, Nancy;
Navarro, Laura;
Wiese, Guillermo;
Cortés-Cortés, Piedad;
Gidekel, Manuel;
Gutierrez-Moraga, Ana;
Salazar, Lorena.
SUMMARY: Cancer is the second leading cause of death in the world and colorectal cancer is the only cancer that has shown a sustained increase in mortality in the last decade. In the search for new chemotherapeutic agents against cancer, extremophilic microorganisms have shown to be a potential source to...
Microbiología del Suelo,
Regiones Antárticas,
Bacillus/fisiología,
Bacillus/aislamiento & purificación,
Bacillus/genética,
Proliferación Celular/efectos de los fármacos,
Neoplasias Colorrectales/tratamiento farmacológico,
Línea Celular Tumoral/efectos de los fármacos,
Supervivencia Celular/efectos de los fármacos,
ARN Ribosómico 16S,
Fenotipo,
Genotipo,
Técnicas In Vitro,
Adenocarcinoma/tratamiento farmacológico,
Reacción en Cadena de la Polimerasa
Devido a constante necessidade de desenvolver materiais biocompatíveis com
propriedades osteocondutores e osteoindutoras, a presente tese conta com o
desenvolvimento de dois estudos in vitro com fibra de carbono obtida a partir de
fibra PAN têxtil, incorporada com diferentes íons de metais, na oste...
