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Short-term creatine supplementation changes protein metabolism signaling in hindlimb suspension

Braz. j. med. biol. res; 52 (10), 2019
The effect of a short-term creatine supplementation on hindlimb suspension (HS)-induced muscle atrophy was investigated. Creatine monohydrate (5 g/kg b.w. per day) or placebo, divided in 2 daily doses, was given by oral gavage for 5 days. Rats were maintained in HS with dietary supplementation concomitan...