ABSTRACT Background: Multiple sclerosis exhibits specific neuropathological phenomena driving to both global and regional brain atrophy. At the clinical level, the disease is related to functional decline in cognitive domains as the working memory, processing speed, and verbal fluency. However, the comp...
Atrofia/patología,
Encéfalo/diagnóstico por imagen,
Encéfalo/patología,
Cognición,
Sustancia Gris/diagnóstico por imagen,
Imagen por Resonancia Magnética,
Esclerosis Múltiple/complicaciones,
Esclerosis Múltiple/diagnóstico por imagen,
Esclerosis Múltiple/patología,
Esclerosis Múltiple Recurrente-Remitente,
Pruebas Neuropsicológicas,
Cognición Social
ABSTRACT The longstanding study of gross anatomy experienced a considerable improvement with the advent of the microscope in the early 17th century. The representative personality of this new era certainly was Marcello Malpighi, seen as "founder of microscopic anatomy". He studied, with a rudimentary com...
Cui, Xiaorui;
Li, Lan;
Yu, Lei;
Xing, Huijuan;
Chang, Hong;
Zhao, Li;
Qian, Jin;
Song, Qingwei;
Zhou, Shiyu;
Dong, Chunbo.
OBJECTIVES: Parkinson's disease (PD) and the parkinsonian variant of multiple system atrophy (MSA-P) are distinct neurodegenerative disorders that share similar clinical features of parkinsonism. The morphological alterations of these diseases have yet to be understood. The purpose of this study was to e...
Buchpiguel, Marina;
Rosa, Pedro;
Squarzoni, Paula;
Duran, Fabio L S;
Tamashiro-Duran, Jaqueline H;
Leite, Claudia C;
Lotufo, Paulo;
Scazufca, Marcia;
Alves, Tania C T F;
Busatto, Geraldo F.
OBJECTIVES: Although a large number of studies have shown brain volumetric differences between men and women, only a few investigations have analyzed brain tissue volumes in representative samples of the general elderly population. We investigated differences in gray matter (GM) volumes, white matter (WM...
Evidence from previous voxel-based morphometry (VBM) studies indicates that widespread brain regions are involved in Parkinson's disease with mild cognitive impairment (PD-MCI). However, the spatial localization reported for gray matter (GM) abnormalities is heterogeneous. The aim of the present study wa...
While various neurodegenerative diseases affect cortical mass differently, finding an optimal and accurate method for measuring the thickness and surface area of cerebral cortex remains a challenging problem due to highly convoluted surface of the cortex. We therefore investigated cortical thickness in a...
Abstract Introduction: Bipolar disorder (BD) is a debilitating mood condition that affects approximately 1.3% of people worldwide, although some studies report up to 3.9% lifetime prevalence and 4-6% in adults when broad diagnostic criteria are applied. Objective: To compare differences in total white ...
Trastorno Bipolar/diagnóstico por imagen,
Trastorno Bipolar/patología,
Estudios de Casos y Controles,
Cuerpo Calloso/diagnóstico por imagen,
Cuerpo Calloso/patología,
Progresión de la Enfermedad,
Sustancia Gris/diagnóstico por imagen,
Sustancia Gris/patología,
Imagen por Resonancia Magnética,
Persona de Mediana Edad,
Tamaño de los Órganos,
Sustancia Blanca/diagnóstico por imagen,
Sustancia Blanca/patología
ABSTRACT Background: Virtual reality therapy (VRT) is an interactive intervention that induces neuroplasticity. The aim was to evaluate the effects of VRT associated with conventional rehabilitation for an upper limb after stroke, and the neuroimaging predictors of a better response to VRT. Methods: Pa...
Actividades Cotidianas,
Sustancia Gris/lesiones,
Cápsula Interna/lesiones,
Neuroimagen/métodos,
Estudios Prospectivos,
Calidad de Vida,
Recuperación de la Función,
Índice de Severidad de la Enfermedad,
Accidente Cerebrovascular/diagnóstico,
Rehabilitación de Accidente Cerebrovascular/métodos,
Resultado del Tratamiento,
Extremidad Superior,
Terapia de Exposición Mediante Realidad Virtual/métodos,
Sustancia Blanca/lesiones
La distonía es una entidad pobremente comprendida ya que a pesar que la era genómica ha proporcionado muchas pistas para la elucidación de los circuitos cerebrales responsables de este fenómeno, aún resta mucho por entender debido a que los modelos actuales son insuficientes para comprender a cabali...
Objective: Approximately one-half of all patients affected by bipolar disorder present with psychotic features on at least one occasion. Several studies have found that alterations in the activity of mesolimbic and prefrontal regions are related to aberrant salience in psychotic patients. The aim of the ...
Trastorno Bipolar/complicaciones,
Trastorno Bipolar/diagnóstico por imagen,
Trastorno Bipolar/fisiopatología,
Corteza Cerebral/diagnóstico por imagen,
Corteza Cerebral/fisiopatología,
Estudios Transversales,
Sustancia Gris/diagnóstico por imagen,
Sustancia Gris/patología,
Alucinaciones/complicaciones,
Alucinaciones/fisiopatología,
Imagen por Resonancia Magnética,
Persona de Mediana Edad,
Tamaño de los Órganos
