Acetaminophen induces alterations to the renal tubular ultrastructure in a rat model of acute nephrotoxicity protected by resveratrol and quercetin
Int. j. morphol; 38 (3), 2020
Acetaminophen (also called paracetamol, or APAP) induced nephrotoxicity is reported after accidental or intentional ingestion of an overdose of the drug. Renal tubular ultrastructural alterations induced by APAP overdose associated with the induction of biomarkers of kidney injury have not been investiga...
Acetaminofén/toxicidad, Túbulos Renales/efectos de los fármacos, Resveratrol/administración & dosificación, Resveratrol/farmacologÃa, Quercetina/administración & dosificación, Quercetina/farmacologÃa, Modelos Animales de Enfermedad, Sobredosis de Droga, Ratas Sprague-Dawley, MicroscopÃa Electrónica de Transmisión, Antioxidantes/administración & dosificación, Antiinflamatorios/administración & dosificación, Urea/sangre, Creatinina/sangre, Túbulos Renales/patologÃa